典型文献
Formation of composite hydrogel of carboxymethyl konjac glucomannan/gelatin for sustained release of EGCG
文献摘要：
Development of functional bioinspired hydrogels that have good releases control character is necessary for the application of these materials in biomedical engineering. Herein, we report a composite hydrogel prepared from several biocompatible carboxymethyl konjac glucomannan (CKGM)/gelatin (G)/tannic acid (TA) functional nano-hydroxyapatite (TA@n-HA), which has good biodegradability and pH sensitivity. The mechanism of interaction between hydrogels was confirmed by Fourier transform infrared spectroscopy, X-ray diffraction, Scanning electron microscopy and Thermogravimetric analysis. The physico-chemical properties of CKGM/G hydrogels have been significantly improved through the incorporation of TA@n-HA within the matrix. Studies in the sustained release of epigallocatechin gallate (EGCG) demonstrated that the TA@n-HA/CKGM/G hydrogels exhibit not only better pH sensitive properties, but also enhanced biocompatibility and encapsulation in comparison to the matrix devoid of TA@n-HA. Consequently, TA@n-HA/CKGM/G hydrogels using EGCG as a drug release model show the potential for drug delivery.
文献关键词：
中图分类号：
作者姓名：
Lin Wang;Ning zhou;Shengxuan Zheng;Jie Pang
作者机构：
Department of Engineering Mechanics,Tsinghua University,Beijing 100084,China;Institute of Superlubricity Technology,Research Institute of Tsinghua University in Shenzhen,Shenzhen 518057,China;College of Food Science,Fujian Agriculture and Forestry University,Fuzhou 350002,China
文献出处：
引用格式：
[1]Lin Wang;Ning zhou;Shengxuan Zheng;Jie Pang-.Formation of composite hydrogel of carboxymethyl konjac glucomannan/gelatin for sustained release of EGCG)[J].食品科学与人类健康（英文）,2022(05):1373-1383
A类：
CKGM
B类：
Formation,composite,carboxymethyl,konjac,glucomannan,gelatin,sustained,EGCG,Development,functional,bioinspired,hydrogels,that,have,good,releases,control,character,necessary,application,these,materials,biomedical,engineering,Herein,report,prepared,from,several,biocompatible,tannic,acid,TA,nano,hydroxyapatite,HA,which,has,biodegradability,sensitivity,mechanism,interaction,between,was,confirmed,by,Fourier,transform,infrared,spectroscopy,ray,diffraction,Scanning,electron,microscopy,Thermogravimetric,analysis,physico,chemical,properties,been,significantly,improved,through,incorporation,within,matrix,Studies,epigallocatechin,gallate,demonstrated,exhibit,not,only,better,sensitive,but,also,enhanced,biocompatibility,encapsulation,comparison,devoid,Consequently,using,drug,model,show,potential,delivery
AB值：
0.61139
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
