典型文献
A new Lactobacillus gasseri strain HMV18 inhibits the growth of pathogenic bacteria
文献摘要：
To search for a new eco-friendly therapy for infectious disease caused by Escherichia coli,Staphylococcus aureus or Klebsiella oxytoca,we collected the vaginal swabs from healthy women,screened for Lactobacillus and found a strain repressing the growth of pathogenic bacteria.The new isolate was identified as L.gasseri by the colony morphology,Gram staining,biochemical reactions and confirmed by the 16S rDNA sequencing.The HMV18 strain inhibited the growth of food-borne pathogens such as E.coli,S.aureus and K.oxytoca.The HMV18 strain was sensitive to penicillin,ampicillin,erythromycin,tetracycline and chloramphenicol.The HMV18 strain produced a-hemolysis.Pathological histology of the mice ileum showed that the mucosa,villi,lamina propria and crypt depth remained intact and there was no inflammation or hyperemia in the L.gasseri HMV18 gavaged group.L.gasseri HMV18 could not up-regulate inflammatory cytokines level of plasma.All the results suggested L.gasseri HMV18 is a candidate probiotic to be an additive for food preservation or drug to prevent food-borne diseases.
文献关键词：
中图分类号：
作者姓名：
Xiang Gao;Zixuan Wang;Xiang Li;Xiaoling Zhang;Shengqiang Du;Miaomiao Jia;Dailun Hu;Xianxian Jia;Bin Cong;Yan Zhang;Chunling Ma;Song Zhou;Jun Zhang
作者机构：
Department of Pathogen Biology,Institute of Basic Medicine,Hebei Medical University,Shijiazhuang 050017,China;Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences,Shijiazhuang 050017,China;Institute of Basic Medicine,Hebei Medical University,Shijiazhuang 050017,China;Shijiazhuang Great Wall Integrated Traditional Chinese and Western Medicine Hospital,Shijiazhuang 050035,China;College of Forensic Medicine,Hebei Key Laboratory of Forensic Medicine,Collaborative Innovation Center of Forensic Medical Molecular Identification,Hebei Medical University,Shijiazhuang 050017,China;Hebei Food Safety Key Laboratory,Hebei Food Inspection and Research Institute,Shijiazhuang 050227,China
文献出处：
引用格式：
[1]Xiang Gao;Zixuan Wang;Xiang Li;Xiaoling Zhang;Shengqiang Du;Miaomiao Jia;Dailun Hu;Xianxian Jia;Bin Cong;Yan Zhang;Chunling Ma;Song Zhou;Jun Zhang-.A new Lactobacillus gasseri strain HMV18 inhibits the growth of pathogenic bacteria)[J].食品科学与人类健康（英文）,2022(02):247-254
A类：
HMV18
B类：
new,Lactobacillus,gasseri,strain,inhibits,growth,pathogenic,bacteria,To,search,eco,friendly,therapy,infectious,caused,by,Escherichia,coli,Staphylococcus,aureus,Klebsiella,oxytoca,collected,vaginal,swabs,from,healthy,women,screened,found,repressing,isolate,was,identified,colony,morphology,Gram,staining,biochemical,reactions,confirmed,16S,rDNA,sequencing,inhibited,food,borne,pathogens,such,sensitive,penicillin,ampicillin,erythromycin,tetracycline,chloramphenicol,produced,hemolysis,Pathological,histology,mice,ileum,showed,that,mucosa,villi,lamina,propria,crypt,depth,remained,intact,there,inflammation,hyperemia,gavaged,group,could,not,regulate,inflammatory,cytokines,level,plasma,All,results,suggested,candidate,probiotic,be,additive,preservation,drug,prevent,diseases
AB值：
0.620059
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