典型文献
Anti-inflammatory and analgesic properties of Moroccan medicinal plants:Phytochemistry,in vitro and in vivo investigations,mechanism insights,clinical evidences and perspectives
文献摘要:
Moroccan medicinal plants exhibit several pharmacological properties such as antimicrobial,anticancer,antidiabetic,analgesic,and anti-inflammatory effects,which are related to the presence of numerous bioactive compounds,including phenolic acids,flavonoids,and terpenoids.In the present review,we systematically evaluate previously published reports on the anti-inflammatory and analgesic effects of Moroccan medicinal plants.The in vitro investigations revealed that Moroccan medicinal plants inhibit several enzymes related to inflammatory processes,whereas in vivo studies noted significant anti-inflammatory and analgesic effects as demonstrated using different experimental models.Various bioactive compounds exhibiting in vitro and in vivo anti-inflammatory and analgesic effects,with diverse mechanisms of action,have been identified.Some plants and their bioactive compounds reveal specific secondary metabolites that possess important anti-inflammatory effects in clinical investigations.Our review proposes the potential applications of Moroccan medicinal plants as sources of anti-inflammatory and analgesic agents.
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中图分类号:
作者姓名:
Abdelhakim Bouyahya;Fatima-Ezzahrae Guaouguaou;Nasreddine El Omari;Naoual El Menyiy;Abdelaali Balahbib;Mohamed El-Shazly;Youssef Bakri
作者机构:
Laboratory of Human Pathologies Biology,Department of Biology,Faculty of Sciences,and Genomic Center of Human Pathologies,Faculty of Medicine and Pharmacy,Mohammed V University in Rabat,4014,Morocco;Mohammed V University in Rabat,LPCMIO,Materials Science Center(MSC),Ecole Normale Supérieure,Rabat,1014,Morocco;Laboratory of Histology,Embryology and Cytogenetic,Faculty of Medicine and Pharmacy,Mohammed V University in Rabat,10100,Morocco;Department of Biology,Faculty of Sciences Dhar El Mahraz,University Sidi Mohamed Ben Abdellah,Fez,30003,Morocco;Laboratory of Zoology and General Biology,Faculty of Sciences,Mohammed V University in Rabat,Rabat,1014,Morocco;Department of Pharmacognosy,Faculty of Pharmacy,Ain-Shams University,Cairo,11566,Egypt;Department of Pharmaceutical Biology,Faculty of Pharmacy and Biotechnology,German University in Cairo,Cairo,11835,Egypt
文献出处:
引用格式:
[1]Abdelhakim Bouyahya;Fatima-Ezzahrae Guaouguaou;Nasreddine El Omari;Naoual El Menyiy;Abdelaali Balahbib;Mohamed El-Shazly;Youssef Bakri-.Anti-inflammatory and analgesic properties of Moroccan medicinal plants:Phytochemistry,in vitro and in vivo investigations,mechanism insights,clinical evidences and perspectives)[J].药物分析学报(英文),2022(01):35-57
A类:
Phytochemistry
B类:
Anti,inflammatory,analgesic,properties,Moroccan,medicinal,plants,vitro,vivo,investigations,insights,clinical,evidences,perspectives,several,pharmacological,such,antimicrobial,anticancer,antidiabetic,effects,which,are,related,presence,numerous,bioactive,compounds,including,phenolic,acids,flavonoids,terpenoids,In,present,review,we,systematically,evaluate,previously,published,reports,revealed,that,inhibit,enzymes,processes,whereas,studies,noted,significant,demonstrated,using,different,experimental,models,Various,exhibiting,diverse,mechanisms,action,have,been,identified,Some,their,specific,secondary,metabolites,possess,important,Our,proposes,potential,applications,sources,agents
AB值:
0.503543
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