典型文献
Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature
文献摘要:
Laser speckle imaging has been widely used for in-vivo visualization of blood perfusion in biological tissues. However, existing laser speckle imaging techniques suffer from limited quantification accuracy and spatial resolution. Here we re-port a novel design and implementation of a powerful laser speckle imaging platform to solve the two critical limitations. The core technique of our platform is a combination of line scan confocal microscopy with laser speckle autocorrelation imaging, which is termed Line Scan Laser Speckle Autocorrelation Imaging (LS-LSAI). The technical advantages of LS-LSAI include high spatial resolution (~4.4 μm) for visualizing and quantifying blood flow in microvessels, as well as video-rate imaging speed for tracing dynamic flow.
文献关键词:
中图分类号:
作者姓名:
E Du;Shuhao Shen;Anqi Qiu;Nanguang Chen
作者机构:
Department of Biomedical Engineering,National University of Singapore,7 Engineering Drive 1,Singapore 117574,Singapore
文献出处:
引用格式:
[1]E Du;Shuhao Shen;Anqi Qiu;Nanguang Chen-.Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature)[J].光电进展(英文版),2022(02):22-32
A类:
LSAI
B类:
Confocal,laser,speckle,autocorrelation,imaging,dynamic,flow,microvasculature,Laser,has,been,widely,used,vivo,visualization,blood,perfusion,biological,tissues,However,existing,techniques,suffer,from,limited,quantification,accuracy,spatial,resolution,Here,port,novel,design,implementation,powerful,platform,solve,two,critical,limitations,core,our,combination,line,scan,confocal,microscopy,which,termed,Line,Scan,Speckle,Autocorrelation,Imaging,technical,advantages,include,high,visualizing,quantifying,microvessels,well,video,rate,speed,tracing
AB值:
0.628373
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