典型文献
Celebrating the discovery of DNA demethylaseFA
文献摘要：
Maintaining correct DNA methylation patterns entails the addition of methyl groups by DNA methyltransferases and the active removal of methylation from DNA. Removing a methyl group from 5-methylcytosine requires breaking a strong C–C bond, suggesting that demethylation might occur by an alternative mechanism that does not involve severing this bond. Indeed, the discovery of the 5-methylcytosine DNA glycosylase (also known as DNA demethylase) REPRESSOR OF SILENCING 1 (ROS1) by (Gong et al., 2002) revolutionized thinking in this field, as the study of ROS1 revealed a mechanism by which 5-methylcytosine is excised and replaced by the DNA repair machinery. This special issue celebrates the 20th anniversary of the discovery of ROS1 and the remarkable research that followed.
文献关键词：
中图分类号：
作者姓名：
Zhizhong Gong;Jian-Kang Zhu
作者机构：
State Key Laboratory of Plant Physiology and Biochemistry,College of Biological Sciences,China Agricultural University,Beijing 100193,China;School of Life Sciences,Institute of Life Science and Green Development,Hebei University,Baoding 071002,China;School of Life Sciences,Institute of Advanced Biotechnology,Southern University of Science and Technology,Shenzhen 518055,China
文献出处：
引用格式：
[1]Zhizhong Gong;Jian-Kang Zhu-.Celebrating the discovery of DNA demethylaseFA)[J].植物学报（英文版）,2022(12):2215-2216
A类：
demethylaseFA,severing,REPRESSOR,SILENCING
B类：
Celebrating,discovery,Maintaining,correct,patterns,entails,addition,groups,by,methyltransferases,active,removal,from,Removing,methylcytosine,requires,breaking,strong,bond,suggesting,that,demethylation,might,occur,alternative,mechanism,does,not,involve,this,Indeed,glycosylase,also,known,OF,ROS1,Gong,revolutionized,thinking,field,study,revealed,which,excised,replaced,repair,machinery,This,special,issue,celebrates,20th,anniversary,remarkable,research,followed
AB值：
0.573651
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
