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典型文献
Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection
文献摘要:
Both inflammation and anti-inflammation are involved in the protection of retinal cells.Antagonists of the hypothalamic growth hormone-releasing hormone receptor(GHRHR)have been shown to possess potent anti-inflammatory properties in experimental disease models of various organs,some with systemic complications.Such effects are also found in ocular inflammatory and neurologic injury studies.In experimental models of mice and rats,both growth hormone-releasing hormone receptor agonists and antagonists may alleviate death of ocular neural cells under certain experimental conditions.This review explores the properties of growth hormone-releasing hormone receptor agonists and antagonists that lead to its protection against inflammatory responses induced by extrinsic agents or neurologic injures in ocular animal models.
文献关键词:
作者姓名:
Ling-Ping Cen;Tsz Kin Ng;Wai Kit Chu;Chi Pui Pang
作者机构:
Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong,Shantou,Guangdong Province,China;Shantou University Medical College,Shantou,Guangdong Province,China;Department of Ophthalmology and Visual Sciences,The Chinese University of Hong Kong,Hong Kong Special Administrative Region,China
引用格式:
[1]Ling-Ping Cen;Tsz Kin Ng;Wai Kit Chu;Chi Pui Pang-.Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection)[J].中国神经再生研究(英文版),2022(12):2643-2648
A类:
Antagonists,GHRHR,injures
B类:
Growth,hormone,releasing,receptor,signaling,experimental,ocular,inflammation,neuroprotection,Both,anti,are,involved,retinal,cells,hypothalamic,growth,have,been,shown,possess,potent,inflammatory,properties,disease,models,various,organs,some,systemic,complications,Such,effects,also,found,neurologic,injury,studies,In,mice,rats,both,antagonists,may,alleviate,death,neural,under,certain,conditions,This,review,explores,that,lead,its,against,responses,induced,by,extrinsic,agents,animal
AB值:
0.533477
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