典型文献
The roles of microRNAs in spinal cord ischemia-reperfusion injury
文献摘要：
Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological conditions.However,multiple stimuli can trigger SCII,so the underlying mechanism of this pathology has not yet been fully established.MicroRNAs(miRNAs)are a class of non-coding RNAs that mediate a variety of nervous system diseases and regulate numerous physiological functions,including apoptosis,autophagy,inflammation,and blood-spinal cord barrier damage.miRNA expression profiles are known to be altered after spinal cord ischemia/reperfusion injury.Therefore,gaining a better understanding of the significant roles that miRNAs play in spinal cord ischemia/reperfusion injury could help develop potential preventive and therapeutic strategies for spinal cord ischemia/reperfusion injury.This review summarizes the current state of our knowledge about the relationship between miRNAs and spinal cord ischemia/reperfusion injury,as well as potential miRNAs that could be targeted to treat spinal cord ischemia/reperfusion injury.
文献关键词：
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作者姓名：
Feng-Shou Chen;Xiang-Yi Tong;Bo Fang;Dan Wang;Xiao-Qian Li;Zai-Li Zhang
作者机构：
Department of Anesthesiology,the First Hospital of China Medical University,Shenyang,Liaoning Province,China
文献出处：
引用格式：
[1]Feng-Shou Chen;Xiang-Yi Tong;Bo Fang;Dan Wang;Xiao-Qian Li;Zai-Li Zhang-.The roles of microRNAs in spinal cord ischemia-reperfusion injury)[J].中国神经再生研究（英文版）,2022(12):2593-2599
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0.575274
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