典型文献
Functional and immunological peculiarities of peripheral nerve allografts
文献摘要：
This review addresses the accumulating evidence that live (not decellularized) allogeneic peripheral nerves are functionally and immunologically peculiar in comparison withmany other transplanted allogeneic tissues. This is relevant because live peripheral nerve allografts are very effective at promoting recovery after segmental peripheral nerve injury via axonal regeneration and axon fusion. Understanding the immunological peculiarities of peripheral nerve allografts may also be of interest to the field of transplantation in general. Three topics are addressed: The first discusses peripheral nerve injury and the potential utility of peripheral nerve allografts for bridging segmental peripheral nerve defects via axon fusion and axon regeneration. The second reviews evidence that peripheral nerve allografts elicit a more gradual and less severe host immune response allowing for prolonged survival and function of allogeneic peripheral nerve cells and structures. Lastly, potential mechanisms that may account for the immunological differences of peripheral nerve allografts are discussed.
文献关键词：
中图分类号：
作者姓名：
Kelly C.S.Roballo
作者机构：
School of Pharmacy,University of Wyoming,Laramie,WY,USA;Department of Molecular Biology,University of Wyoming,Laramie,WY,USA;Department of Molecular Biosciences,University of Texas at Austin,Austin,TX,USA;Department of Neuroscience,University of Texas at Austin,Austin,TX,USA
文献出处：
引用格式：
[1]Kelly C.S.Roballo-.Functional and immunological peculiarities of peripheral nerve allografts)[J].中国神经再生研究（英文版）,2022(04):721-727
A类：
immunologically,withmany
B类：
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AB值：
0.474839
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
