Surface-enhanced Raman scattering(SERS)spectroscopy has been employed as a rapid analysis technol-ogy for food security inspection recently.Nowadays,it is still a great challenge to rapidly quantify multi-ple trace antibiotics potentially abused in aquaculture industry.In this work,a magnetic Ti3C2Tx/Fe3O4/Ag substrate was prepared for the development of a reliable rapid SERS quantification method for multi-ple trace sulfonamides in aquatic products.This magnetic substrate had good uniformity,reproducibility,stability and SERS activity.Moreover,this substrate could integrate the magnetic separation-enrichment and matrix clean-up without cross contamination,which endowed it with good selectivity and anti-interference capability during real sample analysis.The electromagnetic enhancement and chemical en-hancement mechanism of this magnetic substrate were studied in detail to reveal its good separation-enrichment performance and SERS activity.Finally,a rapid SERS quantification method was established and practically applied for trace phthalic sulfathiazole(PST)and silver sulfadiazine(SSD)in aquatic prod-ucts by using Ti3C2Tx/Fe3O4/Ag magnetic substrates.Trace PST and SSD could be actually detected and quantified as 55.9μg/kg and 64.0μg/kg in aquatic products,respectively.Good recoveries of 83.9％-116％with relative standard deviations(RSDs)of 0.5％-3.2％for PST and 80.2％-102％with RSDs of 1.3％-5.8％for SSD were obtained.This work proposed an efficient and reliable method for rapid quantification of trace multiple sulfonamides in complex aquatic samples during food security inspection.

Zhongning Yu;Lu Huang;Zhuomin Zhang;Gongke Li

School of Chemistry,Sun Yat-sen University,Guangzhou 510275,China

中国化学快报（英文版）

[1]Zhongning Yu;Lu Huang;Zhuomin Zhang;Gongke Li-.Magnetic Ti3C2Tx/Fe3O4/Ag substrate for rapid quantification of trace sulfonamides in aquatic products by surface enhanced Raman spectroscopy)[J].中国化学快报（英文版）,2022(08):3853-3858

abused,sulfathiazole

Magnetic,Ti3C2Tx,Fe3O4,Ag,quantification,trace,sulfonamides,aquatic,products,by,surface,enhanced,Raman,spectroscopy,Surface,scattering,SERS,has,been,employed,analysis,technol,ogy,food,security,inspection,recently,Nowadays,still,great,challenge,rapidly,quantify,antibiotics,potentially,aquaculture,industry,In,this,work,was,prepared,development,reliable,method,This,had,good,uniformity,reproducibility,stability,activity,Moreover,could,integrate,separation,enrichment,matrix,clean,up,without,cross,contamination,which,endowed,selectivity,interference,capability,during,real,electromagnetic,enhancement,chemical,mechanism,were,studied,detail,reveal,its,performance,Finally,established,practically,applied,phthalic,PST,silver,sulfadiazine,SSD,using,substrates,Trace,actually,detected,quantified,respectively,Good,recoveries,relative,standard,deviations,RSDs,obtained,proposed,efficient,multiple,complex,samples

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