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典型文献
Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus
文献摘要:
Seahorse embryos are brooded in the enclosed nutrient-rich environment of the male brood pouch, which may be prone to bacterial infection. The immune responses of interleukin (IL) genes in the brood pouch have not been well studied. We identified 13 interleukins in the lined seahorse Hippocampus erectus . Tissue-specific expression analysis revealed increased mRNA expression levels of il - 1β , il - 18 , and il - 8 in the brood pouch. When challenged with lipopolysaccharide or Vibrio parahaemolyticus , il - 1β and il - 18 were active as part of the acute and chronic inflammatory responses, respectively. Importantly, il - 8 may be involved in powerful antibacterial immune responses and may be induced by il - 1β and il - 18 via a process involving the nuclear factor-κB signaling pathway. These results suggest that il - 1β , il - 18 , and il - 8 may play key roles in the antibacterial immune defense of the brood pouch in male seahorses.
文献关键词:
作者姓名:
Han JIANG;Chunyan LI;Bo ZHANG;Yongli WU;Qiang LIN
作者机构:
CAS Key Laboratory of Tropical Marine Bio-resources and Ecology,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China;Guangdong Provincial Key Laboratory of Applied Marine Biology,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China;University of Chinese Academy of Sciences,Beijing 100049,China
引用格式:
[1]Han JIANG;Chunyan LI;Bo ZHANG;Yongli WU;Qiang LIN-.Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus)[J].海洋湖沼学报(英文版),2022(01):235-244
A类:
erectus,brooded,seahorses
B类:
Roles,interleukins,antibacterial,immune,defense,pouch,lined,Hippocampus,Seahorse,embryos,are,enclosed,nutrient,rich,environment,male,which,may,prone,infection,responses,genes,have,not,been,well,studied,We,identified,Tissue,specific,expression,analysis,revealed,increased,levels,il,When,challenged,lipopolysaccharide,Vibrio,parahaemolyticus,were,active,part,acute,chronic,inflammatory,respectively,Importantly,involved,powerful,induced,by,via,process,involving,nuclear,signaling,pathway,These,results,suggest,that,play,key,roles
AB值:
0.441276
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