典型文献
Dietary fat intake and liver cancer risk: A prospective cohort study in Chinese women
文献摘要:
Objective: This study aimed to determine whether dietary fat intake increased liver cancer risk in Chinese women from a prospective population-based cohort. Methods: A total of 72,704 Chinese women were followed up from the time of baseline recruitment (1996-2000) to the end of 2016. Dietary fat intake was calculated using a validated food frequency questionnaire. The Cox regression model was used to assess the hazard ratio (HR) and 95% confidence intervals (CI) for dietary fat intake and liver cancer risk. Results: We identified 252 incident liver cancer cases out of 1,267,845 person-years during the overall follow-up time. Null associations, neither in quartiles nor per standard deviation (SD) increment, were detected between liver cancer risk and dietary total fat, fat subtypes and subtype ratios, and food sources. The HR (95% CI) of the 1-SD increment was 1.03 (0.90-1.17) for total fat, 1.06 (0.93-1.20) for saturated fat, 1.06 (0.93-1.21) for monounsaturated fat, and 1.00 (0.89-1.13) for polyunsaturated fat. Similar null associations were observed in stratification analyses according to body mass index and menopausal status. Conclusions: In our prospective cohort study, no significant association was observed in Chinese women between dietary fat and liver cancer risk, and in stratification and sensitivity analyses.
文献关键词:
中图分类号:
作者姓名:
Xiaowei Ji;Jing Wang;Zhuoying Li;Qiuming Shen;Jiayi Tuo;Jinghao Bi;Yuting Tan;Honglan Li;Yongbing Xiang
作者机构:
State Key Laboratory of Oncogene and Related Genes&Department of Epidemiology,Shanghai Cancer Institute,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200032,China;School of Public Health,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
文献出处:
引用格式:
[1]Xiaowei Ji;Jing Wang;Zhuoying Li;Qiuming Shen;Jiayi Tuo;Jinghao Bi;Yuting Tan;Honglan Li;Yongbing Xiang-.Dietary fat intake and liver cancer risk: A prospective cohort study in Chinese women)[J].癌症生物学与医学(英文版),2022(03):370-383
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0.489004
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