No information is available regarding the utilization of iron(Fe)from different Fe sources at a target tissue level.To detect differences in Fe metabolic utilization among Fe sources,the effect of intravenously injected Fe on growth performance,hematological indices,tissue Fe concentrations and Fe-containing enzyme activities and gene expressions of Fe-containing enzymes or protein in broilers was investi-gated.On d 22 post-hatching,a total of 432 male chickens were randomly allotted to 1 of 9 treatments in a completely randomized design.Chickens were injected with either a 0.9％(wt/vol)NaCl solution(control)or a 0.9％NaCl solution supplemented with Fe sulphate or 1 of 3 organic Fe sources.The 3 organic Fe sources were Fe chelates with weak(Fe-MetW),moderate(Fe-ProtM)or extremely strong(Fe-ProtES)chelation strength.The 2 Fe dosages were calculated according to the Fe absorbabilities of 10％and 20％every 2 d for a duration of 20 d.Iron injection did not affect(P＞0.05)ADFI,ADG or FCR during either 1 to 10 d or 11 to 20 d after injections.Hematocrit and Fe concentrations in the liver and kidney on d 10 after Fe injections,and Fe concentrations in the liver or pancreas and ferritin heavy-chain(FTH1)protein expression level in the liver or spleen on d 20 after Fe injections increased(P＜0.05)as injected Fe dosages increased.When the injected Fe level was high at 20％Fe absorbability,the chickens injected with Fe-ProtES had lower(P＜0.001)liver or kidney Fe concentrations and spleen FTH1 protein levels than those injected with Fe-MetW or Fe-ProtM on d 20 after injections.And they had lower(P＜0.05)liver cytochrome C oxidase mRNA levels on d 20 after injections than those injected with Fe-MetW or Fe sulphate.The results from this study indicate that intravenously injected Fe from Fe-ProtES was the least utilizable and functioned in the sensitive target tissue less effectively than Fe from Fe sulfate,Fe-MetW or Fe-ProtM.

Lin Lu;Xueyu Dong;Xuelian Ma;Liyang Zhang;Sufen Li;Xugang Luo;Xiudong Liao

Mineral Nutrition Research Division,State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing,100193,China;Department of Animal Science,Hebei Normal University of Science and Technology,Qinhuangdao,066004,China;Poultry Mineral Nutrition Laboratory,College of Animal Science and Technology,Yangzhou University,Yangzhou,225000,China

动物营养（英文）

[1]Lin Lu;Xueyu Dong;Xuelian Ma;Liyang Zhang;Sufen Li;Xugang Luo;Xiudong Liao-.Metabolic utilization of intravenously injected iron from different iron sources in target tissues of broiler chickens)[J].动物营养（英文）,2022(02):74-83

Chickens,chelates,MetW,ProtM,ProtES,absorbabilities,utilizable

Metabolic,utilization,intravenously,injected,iron,from,different,sources,target,tissues,chickens,No,information,available,regarding,To,detect,differences,metabolic,among,growth,performance,hematological,indices,concentrations,containing,activities,gene,expressions,enzymes,protein,broilers,was,investi,gated,On,post,hatching,total,male,were,randomly,allotted,treatments,completely,randomized,design,either,vol,NaCl,solution,control,supplemented,sulphate,organic,weak,moderate,extremely,strong,chelation,strength,dosages,calculated,according,every,duration,Iron,did,not,affect,ADFI,ADG,FCR,during,after,injections,Hematocrit,liver,kidney,pancreas,ferritin,heavy,chain,FTH1,spleen,increased,When,high,absorbability,had,lower,levels,than,those,And,they,cytochrome,oxidase,results,this,study,indicate,that,least,functioned,sensitive,less,effectively,sulfate

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