典型文献
Bioinspired Injectable Self-Healing Hydrogel Sealant with Fault-Tolerant and Repeated Thermo-Responsive Adhesion for Sutureless Post-Wound-Closure and Wound Healing
文献摘要：
Hydrogels with multifunctionalities,including sufficient bonding strength,injectability and self-healing capac-ity,responsive-adhesive ability,fault-tolerant and repeated tissue adhesion,are urgently demanded for invasive wound closure and wound healing.Motivated by the adhesive mechanism of mus-sel and brown algae,bioinspired dynamic bonds cross-linked multifunctional hydrogel adhesive is designed based on sodium alginate(SA),gelatin(GT)and protocatechualdehyde,with fer-ric ions added,for sutureless post-wound-closure.The dynamic hydrogel cross-linked through Schiff base bond,catechol-Fe coor-dinate bond and the strong interaction between GT with temper-ature-dependent phase transition and SA,endows the resulting hydrogel with sufficient mechanical and adhesive strength for effi-cient wound closure,injectability and self-healing capacity,and repeated closure of reopened wounds.Moreover,the temperature-dependent adhesive properties endowed mispositioning hydrogel to be removed/repositioned,which is conducive for the fault-tolerant adhesion of the hydrogel adhesives during surgery.Besides,the hydrogels present good biocompatibility,near-infrared-assisted photothermal antibacterial activity,antioxidation and repeated thermo-responsive reversible adhesion and good hemostatic effect.The in vivo incision closure evaluation demonstrated their capability to promote the post-wound-closure and wound healing of the incisions,indicating that the developed reversible adhesive hydrogel dressing could serve as versatile tissue sealant.
文献关键词：
中图分类号：
作者姓名：
Yuqing Liang;Huiru Xu;Zhenlong Li;Aodi Zhangji;Baolin Guo
作者机构：
State Key Laboratory for Mechanical Behavior of Materials,and Frontier Institute of Science and Technology,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China;Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research,College of Stomatology,Xi'an Jiaotong University,Xi'an 710049,People's Republic of China
文献出处：
引用格式：
[1]Yuqing Liang;Huiru Xu;Zhenlong Li;Aodi Zhangji;Baolin Guo-.Bioinspired Injectable Self-Healing Hydrogel Sealant with Fault-Tolerant and Repeated Thermo-Responsive Adhesion for Sutureless Post-Wound-Closure and Wound Healing)[J].纳微快报（英文）,2022(11):256-274
A类：
Sealant,Sutureless,multifunctionalities,sutureless,mispositioning,incisions
B类：
Bioinspired,Injectable,Self,Healing,Fault,Tolerant,Repeated,Thermo,Responsive,Adhesion,Post,Wound,Closure,Hydrogels,including,sufficient,bonding,strength,injectability,self,healing,responsive,fault,tolerant,repeated,tissue,adhesion,urgently,demanded,invasive,closure,Motivated,by,mechanism,mus,brown,algae,bioinspired,dynamic,bonds,cross,linked,designed,sodium,alginate,SA,gelatin,GT,protocatechualdehyde,fer,ric,added,post,through,Schiff,catechol,coor,dinate,strong,interaction,between,dependent,phase,transition,endows,resulting,mechanical,effi,capacity,reopened,wounds,Moreover,temperature,properties,endowed,removed,repositioned,which,conducive,adhesives,during,surgery,Besides,hydrogels,present,good,biocompatibility,near,infrared,assisted,photothermal,antibacterial,activity,antioxidation,thermo,reversible,hemostatic,effect,vivo,evaluation,demonstrated,their,capability,promote,indicating,that,developed,dressing,could,serve,versatile,sealant
AB值：
0.538729
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