典型文献
Fabrication and characterization of hierarchical porous Ni2+doped hydroxyapatite microspheres and their enhanced protein adsorption capacity
文献摘要：
Hydroxyapatite(HAP)is a common bio-adsorbent,which performance depends heavily upon its mor-phology and microporous structure.In this study,a novel synthesis strategy was proposed for hierarchi-cal porous HAP microspheres by a simple"one-pot"hydrothermal reaction.In the strategy,L-glutamic acid serves as soft template to modulate the morphology and inner crystalline of HAP.To evaluate the application potential,doping Ni2+on hierarchical porous HAP microspheres gives metal chelated affinity adsorbents.The prepared adsorbents show a perfect spherical shape,particles size of 96.6 μm,relatively specific surface area of 48.5 m2·g-1 and hierarchical pores(mesopores:4 nm and macropores:53 nm).By the adsorption evaluation,it reveals that the Ni2+-HAP adsorbents have high adsorption capacities of 275.11 and 97.55 m2·g-1 for hemoglobin and bovine serum albumin,respectively,which is comparable to other similar adsorbent.Therefore,this work provides a promising method for high-efficiency hydrox-yapatite microspheres for proteins purification.
文献关键词：
中图分类号：
作者姓名：
Yaling Li;Hao Ai;Liangzhi Qiao;Yinghong Wang;Kaifeng Du
作者机构：
Department of Pharmaceutical&Biological Engineering,School of Chemical Engineering,Sichuan University,Chengdu 610065,China
文献出处：
引用格式：
[1]Yaling Li;Hao Ai;Liangzhi Qiao;Yinghong Wang;Kaifeng Du-.Fabrication and characterization of hierarchical porous Ni2+doped hydroxyapatite microspheres and their enhanced protein adsorption capacity)[J].中国化学工程学报（英文版）,2022(05):238-247
A类：
Ni2+doped,Ni2+on,yapatite
B类：
Fabrication,characterization,hierarchical,hydroxyapatite,microspheres,their,enhanced,adsorption,capacity,Hydroxyapatite,HAP,common,bio,which,performance,depends,heavily,upon,its,microporous,structure,In,this,study,novel,synthesis,strategy,was,proposed,by,simple,one,hydrothermal,reaction,glutamic,acid,serves,soft,template,modulate,morphology,inner,crystalline,To,evaluate,application,potential,doping,gives,metal,chelated,affinity,adsorbents,prepared,show,perfect,spherical,shape,particles,size,relatively,specific,surface,area,mesopores,macropores,By,evaluation,reveals,that,have,high,capacities,hemoglobin,bovine,serum,albumin,respectively,comparable,similar,Therefore,work,provides,promising,method,efficiency,proteins,purification
AB值：
0.592735
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