典型文献
Single-molecular methodologies for the physical biology of protein machines
文献摘要：
Physical biology is an interdisciplinary field that bridges biology with physical sciences and engineering.Single-molecule physical biology focuses on dynamics of individual biomolecules and complexes,aiming to answering basic questions about their functions and mechanisms.It takes advantages of physical methodologies to gain quantitative un-derstanding of biological processes,often engaging precise physical measurements of reconstructed objects to avoid in-terference from unnecessary complications.In this review,we(i)briefly introduce concepts of single-molecule physical biology,(ii)describe extensively used single-molecule methodologies that have been developed to address key questions in two important objects of single-molecule physical biology,namely,nucleic acid-interacting proteins and membrane-interacting proteins,and(iii)show by a few successful examples how one may use single-molecule methods to deepen our understanding of protein machines.
文献关键词：
中图分类号：
作者姓名：
Shuang Wang;Ying Lu;Ming Li
作者机构：
Beijing National Laboratory for Condensed Matter Physics,Institute of Physics,Chinese Academy of Sciences,Beijing 100190,China
文献出处：
引用格式：
[1]Shuang Wang;Ying Lu;Ming Li-.Single-molecular methodologies for the physical biology of protein machines)[J].中国物理B（英文版）,2022(12):81-89
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Single,molecular,methodologies,physical,biology,machines,Physical,interdisciplinary,field,that,bridges,sciences,engineering,focuses,dynamics,individual,biomolecules,complexes,aiming,answering,basic,questions,about,their,functions,mechanisms,It,takes,advantages,gain,quantitative,biological,processes,often,engaging,precise,measurements,reconstructed,objects,avoid,terference,from,unnecessary,complications,In,this,review,briefly,introduce,concepts,single,describe,extensively,used,have,been,developed,address,key,two,important,namely,nucleic,acid,interacting,proteins,membrane,iii,show,by,few,successful,examples,one,may,methods,deepen,our,understanding
AB值：
0.631661
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