典型文献
Which Is Safer,Chinese Medicine or Western Medicine?Comparative Analysis Based on Chinese Spontaneous Reporting Database
文献摘要：
Objective:To compare the safety differences between Chinese medicine (CM) and Western medicine (WM) based on Chinese Spontaneous Reporting Database (CSRD).Methods:Reports of adverse events (AEs) caused by CM and WM in the CSRD between 2010 and 2011 were selected.The following assessment indicators were constructed:the proportion of serious AEs (PSE),the average number of AEs (ANA),and the coverage rate of AEs (CRA).Further comparisons were also conducted,including the drugs with the most reported serious AEs,the AEs with the biggest report number,and the 5 serious AEs of interest (including death,anaphylactic shock,coma,dyspnea and abnormal liver function).Results:The PSE,ANA and CRA of WM were 1.09,8.23 and 2.35 times higher than those of CM,respectively.The top 10 drugs with the most serious AEs were mainly injections for CM and antibiotics for WM.The AEs with the most reports were rash,pruritus,nausea,dizziness and vomiting for both CM and WM.The proportions of CM and WM in anaphylactic shock and coma were similar.For abnormal liver function and death,the proportions of WM were 5.47 and 3.00 times higher than those of CM,respectively.Conclusion:Based on CSRD,CM was safer than WM at the average level from the perspective of adverse drug reactions.
文献关键词：
中图分类号：
作者姓名：
WEI Jian-xiang;LU Zhi-qiang;FENG Guan-zhong;ZHU Yun-xia
作者机构：
School of Management,Nanjing University of Posts and Telecommunications,Nanjing 210003 ,China;School of Internet of Things,Nanjing University of Posts and Telecommunications,Nanjing 210003 ,China
文献出处：
引用格式：
[1]WEI Jian-xiang;LU Zhi-qiang;FENG Guan-zhong;ZHU Yun-xia-.Which Is Safer,Chinese Medicine or Western Medicine?Comparative Analysis Based on Chinese Spontaneous Reporting Database)[J].中国结合医学杂志（英文版）,2022(02):138-144
A类：
CSRD,anaphylactic
B类：
Which,Is,Safer,Chinese,Medicine,Comparative,Analysis,Based,Spontaneous,Reporting,Database,Objective,To,compare,safety,differences,between,medicine,CM,WM,Methods,Reports,adverse,events,AEs,caused,by,were,selected,following,assessment,indicators,constructed,serious,PSE,average,number,ANA,coverage,rate,CRA,Further,comparisons,also,conducted,including,drugs,most,reported,biggest,interest,death,shock,coma,dyspnea,abnormal,liver,function,Results,times,higher,than,those,respectively,top,mainly,injections,antibiotics,reports,rash,pruritus,nausea,dizziness,vomiting,both,proportions,similar,For,Conclusion,was,safer,level,from,perspective,reactions
AB值：
0.44843
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