典型文献
Application and Prospect of Platelet Multi-omics Technology in Study of Blood Stasis Syndrome
文献摘要：
The abnormality of platelet function plays an important role in the pathogenesis and evolution of blood stasis syndrome (BSS).The explanation of its mechanism is a key scientific issue in the study of cardiovascular and cerebrovascular diseases and treatment.System biology technology provides a good technical platform for further development of platelet multi-omics,which is conducive to the scientific interpretation of the biological mechanism of BSS.The article summarized the pathogenesis of platelets in BSS,the mechanism of action of blood activating and stasis resolving drugs,and the application of genomics,proteomics,and metabonomics in platelet research,and put forward the concept of "plateletomics in BSS".Through the combination and cross-validation of multi-omics technology,it mainly focuses on the clinical and basic research of cardiovascular and cerebrovascular diseases;through the interactive verification of multi-omics technology and system biology,it mainly focuses on the platelet function and secretion system.The article systematically explains the molecular biological mechanism of platelet activation,aggregation,release,and other stages in the formation and development of BSS,and provides a new research idea and method for clarifying the pathogenesis of BSS and the mechanism of action of blood activating and stasis resolving drugs.
文献关键词：
中图分类号：
作者姓名：
LI Ying;SUN Ming-qian;LI Lei;ZHANG Ye-hao;MIAO Lan;LIU Jian-xun
作者机构：
Beijing Key Laboratory of Pharmacology of Chinese Materia Region,Xiyuan Hospital,China Academy of Chinese Medical Sciences,National Clinical Research Center for Chinese Medicine Cardiology,Beijing 100091 ,China
文献出处：
引用格式：
[1]LI Ying;SUN Ming-qian;LI Lei;ZHANG Ye-hao;MIAO Lan;LIU Jian-xun-.Application and Prospect of Platelet Multi-omics Technology in Study of Blood Stasis Syndrome)[J].中国结合医学杂志（英文版）,2022(02):99-105
A类：
Stasis,plateletomics
B类：
Application,Prospect,Platelet,Multi,Technology,Study,Blood,Syndrome,abnormality,function,plays,important,role,pathogenesis,evolution,blood,stasis,syndrome,BSS,explanation,its,mechanism,key,scientific,issue,study,cardiovascular,cerebrovascular,diseases,treatment,System,biology,technology,provides,good,technical,platform,further,development,multi,which,conducive,interpretation,biological,article,summarized,platelets,action,activating,resolving,drugs,application,genomics,proteomics,metabonomics,research,put,forward,concept,Through,combination,cross,validation,mainly,focuses,clinical,basic,through,interactive,verification,secretion,systematically,explains,molecular,activation,aggregation,release,other,stages,formation,new,idea,method,clarifying
AB值：
0.495854
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