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典型文献
Keeping time on liver fibrosis
文献摘要:
Liver fibrosis is a common and deadly consequence of repeated exposure to an insult which can be of varying aetiology including viral(hepatitis),autoimmune or alcohol misuse.Key to the disease is the activation of stellate cells that produce a surfeit of extracellular matrix(ECM)including collagens and fibronectin and express the contractile protein alpha-smooth muscle actin.It is now accepted that to activate these key ECM-producing cells new substrates and energy are needed,through glycolysis this is performed.Recently,Xu et al demonstrated a link between phenotypic conversion,glycolysis and the circa-dian clock[1].
文献关键词:
作者姓名:
Steven O'Reilly
作者机构:
引用格式:
[1]Steven O'Reilly-.Keeping time on liver fibrosis)[J].中国药理学报(英文版),2022(05):1215-1216
A类:
surfeit,circa
B类:
Keeping,liver,fibrosis,Liver,common,deadly,consequence,repeated,exposure,insult,which,can,varying,aetiology,including,viral,hepatitis,autoimmune,alcohol,misuse,Key,disease,activation,stellate,cells,that,produce,extracellular,matrix,ECM,collagens,fibronectin,express,contractile,protein,alpha,smooth,muscle,actin,It,now,accepted,activate,these,key,producing,new,substrates,energy,are,needed,through,glycolysis,this,performed,Recently,Xu,demonstrated,link,between,phenotypic,conversion,dian,clock
AB值:
0.738734
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