典型文献
Comparative transcriptome analysis reveals regional specialization of gene expression in larval silkworm(Bombyx mori)midgut
文献摘要：
Insect midgut plays a central role in food digestion and nutrition absorption.Larval silkworm midgut could be divided into 3 distinct regions based on their morpholog-ical colors.However,it remains rudimentary of regional gene expression and physiological function in larval silkworm midgut.Through transcriptome sequencing of 3 midgut com-partments,a comprehensive analysis of gene expression atlas along the anterior-posterior axis was conducted.Posterior midgut was found transcriptionally divergent from anterior and middle midgut.Differentially expressed gene analysis revealed the regional special-ization of digestive enzyme production,transmembrane transport,chitin metabolism,and hormone regulation in different midgut regions.In addition,gene subsets of pan-midgut and region-specific transcription factors(TFs)along the length of midgut were also iden-tified.The results suggested that homeobox TFs might play an essential role in transcrip-tional variations across the midgut.Altogether,our study provided the first fundamental resource to investigate physiological function and regulation mechanism in larval midgut compartmentalization.
文献关键词：
中图分类号：
作者姓名：
Yunwang Shen;Xiaoqun Zeng;Guanping Chen;Xiaofeng Wu
作者机构：
College of Animal Sciences,Zhejiang University,Hangzhou,China;Key Laboratory of Silkworm and Bee Resource Utilization and Innovation of Zhejiang Province,Hangzhou,China
文献出处：
引用格式：
[1]Yunwang Shen;Xiaoqun Zeng;Guanping Chen;Xiaofeng Wu-.Comparative transcriptome analysis reveals regional specialization of gene expression in larval silkworm(Bombyx mori)midgut)[J].中国昆虫科学（英文版）,2022(05):1329-1345
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Comparative,transcriptome,analysis,reveals,regional,specialization,gene,expression,larval,silkworm,Bombyx,mori,midgut,Insect,plays,central,role,food,digestion,nutrition,absorption,Larval,could,be,divided,into,distinct,regions,their,morpholog,colors,However,remains,rudimentary,physiological,function,Through,sequencing,partments,comprehensive,atlas,along,anterior,posterior,axis,was,conducted,Posterior,found,transcriptionally,divergent,from,middle,Differentially,expressed,revealed,digestive,enzyme,production,transmembrane,transport,chitin,metabolism,hormone,regulation,different,addition,subsets,pan,specific,factors,TFs,length,were,also,iden,tified,results,suggested,that,homeobox,might,essential,variations,across,Altogether,study,provided,first,fundamental,resource,investigate,mechanism,compartmentalization
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0.598341
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