典型文献
Production of the yolk protein precursor vitellogenin is mediated by target of rapamycin(TOR)in the soft tick Ornithodoros moubata(Acari:Argasidae)
文献摘要：
Initiation of vitellogenesis by blood feeding is essential for egg maturation in ticks.Nutrients derived from the blood meal are utilized by female ticks to synthe-size the yolk protein precursor vitellogenin(Vg).Engorged Ornithodoros moubata ticks can synthesize Vg whether mated or virgin,thus O.moubata is an excellent model for studying the relative roles of blood feeding and mating in tick vitellogenesis.Injection of rapamycin into engorged O.moubata resulted in a reduction of ovarian growth and yolk accumulation in the oocytes of mated females.OmVg expression in the midgut and fat body and protein concentrations in the hemolymph significantly decreased in mated ticks after injection with rapamycin,indicating that inhibition of the nutrient-sensing target of rapamycin(TOR)pathway disrupts egg maturation at the levels of Vg expression and synthesis.These results suggest that the TOR-signaling pathway induces vitellogenesis in response to nutritional stimulation after a blood meal in O.moubata and is functionally independent of the mating-induced pathway.
文献关键词：
中图分类号：
作者姓名：
Meryem Behri;Haruki Teshima;Keisuke Kutsuwada;Shoko Nakatake;Mari H.Ogihara;DeMar Taylor
作者机构：
Graduate School of Life and Environmental Sciences,University of Tsukuba,Tsukuba,Ibaraki,Japan;Animal Breeding and Reproduction Research Division,Institute of Livestock and Grassland Science,National Agriculture and Food Research Organization,Tsukuba,Ibaraki,Japan
文献出处：
引用格式：
[1]Meryem Behri;Haruki Teshima;Keisuke Kutsuwada;Shoko Nakatake;Mari H.Ogihara;DeMar Taylor-.Production of the yolk protein precursor vitellogenin is mediated by target of rapamycin(TOR)in the soft tick Ornithodoros moubata(Acari:Argasidae))[J].中国昆虫科学（英文版）,2022(05):1299-1308
A类：
Ornithodoros,moubata,Acari,Argasidae,vitellogenesis,ticks,Engorged,engorged,OmVg
B类：
Production,yolk,protein,precursor,vitellogenin,mediated,by,target,rapamycin,TOR,soft,Initiation,blood,feeding,essential,egg,maturation,Nutrients,derived,from,meal,are,utilized,synthesize,whether,mated,virgin,thus,excellent,model,studying,relative,roles,mating,Injection,into,resulted,reduction,ovarian,growth,accumulation,oocytes,females,expression,midgut,fat,body,concentrations,hemolymph,significantly,decreased,after,injection,indicating,that,inhibition,nutrient,sensing,pathway,disrupts,levels,synthesis,These,results,suggest,signaling,induces,response,nutritional,stimulation,functionally,independent,induced
AB值：
0.419642
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
