典型文献
Disruption of egg-specific protein causes female sterility in Bombyx mori
文献摘要：
Yolk proteins are the main source of nutrients during embryonic and early larval development in oviparous animals.Therefore,vitellogenesis is crucial for repro-duction.The silkworm,Bombyx mori,is a model lepidopteran insect in which there are three yolk proteins:vitellin,30-kDa protein,and egg-specific protein (Esp).In this study,we explored the gene function of Esp through transgenic clustered regularly interspaced palindromic repeats (CRISPR) / CRISPR-associated protein 9 technology-mediated mu-tations in the silkworm.We found that Esp mutation resulted in female sterility but had no effect on male fertility.Female mutants could lay eggs after mating,but the eggs were smaller and lighter colored than those laid by wild-type females.The most important find-ing is that the eggs laid by female mutants did not hatch.Furthermore,we observed stable inheritance of female sterility caused by Esp mutation through successive generations.Thus,Esp encodes a yolk protein that is crucial for female reproductive success and is a potential target for pest control.
文献关键词：
中图分类号：
作者姓名：
Xia Xu;Yao-Hui Wang;Zu-Lian Liu;Yong-Qiang Wang;Lin He;Kai Li;Yong-Ping Huang
作者机构：
Institute of Sericulture and Tea Research,Zhejiang Academy of Agricultural Sciences,Hangzhou,310021,China;Key Laboratory of Insect Developmental and Evolutionary Biology,CAS Center for Excellence in Molecular Plant Sciences,Shanghai Institute of Plant Physiology and Ecology,Chinese Academy of Sciences,Shanghai,200032,China;School of Life Science,East China Normal University,Shanghai,200062,China
文献出处：
引用格式：
[1]Xia Xu;Yao-Hui Wang;Zu-Lian Liu;Yong-Qiang Wang;Lin He;Kai Li;Yong-Ping Huang-.Disruption of egg-specific protein causes female sterility in Bombyx mori)[J].中国昆虫科学（英文版）,2022(01):128-138
A类：
oviparous,vitellogenesis,lepidopteran,vitellin,Esp
B类：
Disruption,specific,causes,sterility,Bombyx,mori,Yolk,proteins,are,main,source,nutrients,during,embryonic,early,larval,development,animals,Therefore,crucial,duction,silkworm,model,insect,which,there,three,yolk,kDa,In,this,study,explored,function,through,transgenic,clustered,regularly,interspaced,palindromic,repeats,CRISPR,associated,technology,mediated,tations,We,found,that,mutation,resulted,but,had,effect,fertility,Female,mutants,could,lay,eggs,after,mating,were,smaller,lighter,colored,than,those,laid,wild,type,females,most,important,find,did,not,hatch,Furthermore,observed,stable,inheritance,caused,successive,generations,Thus,encodes,reproductive,potential,target,pest,control
AB值：
0.551138
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