典型文献
Molecular and serological surveillance of Getah virus in the Xinjiang Uygur Autonomous Region,China,2017-2020
文献摘要：
The Getah virus(GETV),a mosquito-borne RNA virus,is widely distributed in Oceania and Asia.GETV is not the only pathogenic to horses,pigs,cattle,foxes and boars,but it can also cause fever in humans.Since its first re-ported case in Chinese mainland in 2017,the number of GETV-affected provinces has increased to seventeen till now.Therefore,we performed an epidemiologic investigation of GETV in the Xinjiang region,located in northwestern China,during the period of 2017-2020.ELISA was used to analyze 3299 serum samples collected from thoroughbred horse,local horse,sheep,goat,cattle,and pigs,with thoroughbred horse(74.8％),local horse(67.3％),goat(11.7％),sheep(10.0％),cattle(25.1％)and pigs(51.1％)being positive for anti-GETV antibodies.Interestingly,the neutralizing antibody titer in horses was much higher than in other species.Four samples from horses and pigs were positive for GETV according to RT-PCR.Furthermore,from the serum of a local horse,we isolated GETV which was designated as strain XJ-2019-07,and determined its complete genome sequence.From the phylogenetic relationships,it belongs to the Group III lineage.This is the first evidence of GETV associated to domestic animals in Xinjiang.Overall,GETV is prevalent in Xinjiang and probably has been for several years.Since no vaccine against GETV is available in China,detection and monitoring strategies should be improved in horses and pigs,especially imported and farmed,in order to prevent economic losses.
文献关键词：
中图分类号：
作者姓名：
Ning Shi;Xiangshu Qiu;Xinyu Cao;Zhanhai Mai;Xiangyu Zhu;Nan Li;He Zhang;Jinyong Zhang;Zhuoxin Li;Nuerlan Shay;Huijun Lu;Ningyi Jin
作者机构：
College of Veterinary Medicine,Northwest A&F University,Yangling,712100,China;Changchun Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Changchun,130000,China;College of Veterinary Medicine,Xinjiang Agricultural University,Wulumuqi,830052,China
文献出处：
引用格式：
[1]Ning Shi;Xiangshu Qiu;Xinyu Cao;Zhanhai Mai;Xiangyu Zhu;Nan Li;He Zhang;Jinyong Zhang;Zhuoxin Li;Nuerlan Shay;Huijun Lu;Ningyi Jin-.Molecular and serological surveillance of Getah virus in the Xinjiang Uygur Autonomous Region,China,2017-2020)[J].中国病毒学,2022(02):229-237
A类：
foxes,boars,thoroughbred
B类：
Molecular,serological,surveillance,Getah,virus,Xinjiang,Uygur,Autonomous,Region,China,GETV,mosquito,borne,widely,distributed,Oceania,Asia,not,only,pathogenic,horses,pigs,cattle,can,also,cause,fever,humans,Since,its,first,case,Chinese,mainland,number,affected,provinces,has,increased,seventeen,till,now,Therefore,performed,epidemiologic,investigation,region,located,northwestern,during,period,was,used,analyze,serum,samples,collected,from,local,sheep,goat,being,positive,antibodies,Interestingly,neutralizing,antibody,titer,much,higher,than,other,species,Four,were,according,Furthermore,isolated,which,designated,strain,XJ,determined,complete,genome,sequence,From,phylogenetic,relationships,belongs,Group,III,lineage,This,evidence,associated,domestic,animals,Overall,prevalent,probably,been,several,years,vaccine,against,available,detection,monitoring,strategies,should,improved,especially,imported,farmed,order,prevent,economic,losses
AB值：
0.535574
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