典型文献
Shaping the sinuses:a novel Krt14+Ctsk+cell lineage driving regenerative bone formation
文献摘要:
The specific skeletal cell types involved in bone formation around the sinus remain unclear.In a recent paper published in Cell Research,Weng et al.identify a novel lineage with mixed epithelial and osteoblast features that mediates bone formation in regenerative procedures involving the maxillary sinus.
The past few years have seen a revolution in defining the cell types forming the skeleton.The field has moved from defining cells based on morphology towards a combination of using cre-based genetic markers to label specific lineages and cell surface markers to define discrete cell types within those lineages.This work has led not only to increasingly precise definitions of skeletal stem cells,1-3 but moreover to an understanding that bone is not formed by a single stem/progenitor cell,but rather through the combined actions of several distinct lineages of stem and progenitor cell types,each with distinct anatomic location and physiologic function.
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中图分类号:
作者姓名:
Seoyeon Bok;Matthew B.Greenblatt
作者机构:
Department of Pathology and Laboratory Medicine,Weill Cornell Medicine,New York,NY,USA;Research Division,Hospital for Special Surgery,New York,NY,USA
文献出处:
引用格式:
[1]Seoyeon Bok;Matthew B.Greenblatt-.Shaping the sinuses:a novel Krt14+Ctsk+cell lineage driving regenerative bone formation)[J].细胞研究(英文版),2022(09):791-792
A类:
Krt14+Ctsk+cell,Weng
B类:
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The,past,few,years,have,seen,revolution,defining,forming,skeleton,field,has,moved,from,cells,morphology,towards,combination,using,genetic,markers,label,lineages,surface,define,discrete,within,those,This,work,led,not,only,increasingly,precise,definitions,stem,but,moreover,understanding,formed,by,single,progenitor,rather,through,combined,actions,several,distinct,each,anatomic,location,physiologic,function
AB值:
0.607558
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