OBJECTIVE To evaluate the safety and efficacy of transcatheter mitral valve repair (TMVR) using MitraClip? devices in oldest-old patients compared to younger patients.METHODS The study retrospectively included 340 consecutive patients who underwent TMVR. Patients were classified acc-ording to age into the oldest-old (age ≥ 85 years) patient group or the younger (age < 85 years) patient group. Immediate results of the procedure, intrahospital outcomes and one-year outcomes were compared. RESULTS Oldest-old patients represented 15.9％ (n = 54) of all patients. Procedure success was comparable for the oldest-old patient group and the younger patient group (92.6％ vs. 95.8％, P = 0.30), and there was no difference in intrahospital mortality (9.2％ vs. 4.2％, P = 0.12). At a one-year follow-up (interquartile range: 6–16 months), there was no significant difference in rehospi-talization due to decompensated heart failure (25.5％ vs. 34.3％, P = 0.24) or all-cause mortality (29.8％ vs. 22.2％, P = 0.26) between the oldest-old patient group and the younger patient group. In patients with available echocardiographic follow-up, severity of residual mitral regurgitation was also comparable between the oldest-old patient group and the younger patient group. CONCLUSIONS TMVR seems to be feasible and effective in oldest-old patients and should be considered for oldest-old pati-ents presenting with symptomatic severe mitral regurgitation and high surgical risk.

Mhd Nawar Alachkar;Annemarie Kirschfink;Anas Alnaimi;J?rg Schr?der;Felix Vogt;Nikolaus Marx;Ertunc Altiok;Mohammad Almalla

Department of Cardiology and Angiology,REGIOMED Hospital Coburg,Coburg,Germany;Department of Cardi-ology,Angiology and Intensive Care,Medical Clinic I,University Hospital RWTH Aachen,Aachen,Germany

老年心脏病学杂志（英文版）

[1]Mhd Nawar Alachkar;Annemarie Kirschfink;Anas Alnaimi;J?rg Schr?der;Felix Vogt;Nikolaus Marx;Ertunc Altiok;Mohammad Almalla-.Transcatheter mitral valve repair is feasible and effective in oldest-old patients: results from real-world cohort)[J].老年心脏病学杂志（英文版）,2022(10):761-767

ording,intrahospital,rehospi,talization,pati

Transcatheter,mitral,valve,repair,feasible,effective,oldest,patients,results,from,real,world,cohort,OBJECTIVE,To,evaluate,safety,efficacy,transcatheter,TMVR,using,MitraClip,devices,compared,younger,METHODS,study,retrospectively,included,consecutive,who,underwent,Patients,were,classified,acc,age,into,years,group,Immediate,procedure,outcomes,one,RESULTS,Oldest,represented,all,Procedure,success,was,comparable,there,no,difference,mortality,At,follow,interquartile,range,months,significant,due,decompensated,heart,failure,cause,between,In,available,echocardiographic,severity,residual,regurgitation,also,CONCLUSIONS,seems,should,considered,presenting,symptomatic,severe,high,surgical,risk

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