典型文献
Evaluation of individualized treatment of nonproliferative diabetic retinopathy:a multicenter,randomized,parallel-controlled study
文献摘要：
OBJECTIVE:To evaluate the differences in the efficacy of stationary treatment and individualized treatment for patients with nonproliferative diabetic retinopathy(NPDR).METHODS:This study was a randomized,controlled,multicenter clinical trial.Participants with NPDR were randomized into the stationary treatment group or the individualized treatment group.The stationary treatment group was given the basic treatment and Qiming granules,and the individualized treatment group was given the basic treatment,Qiming granules,and individualized Chinese herbal medicines over a 12-week period.The individualized therapeutic formula was also changed over time to adjust to the changes in the clinical presentation of the patient.We conducted observations of fundus retinal exudation and hemorrhage,visual acuity,Traditional Chinese Medicine symptom scores and other indicators.RESULTS:A total of 140 participants with NPDR were randomized into the stationary treatment group or the individualized treatment group,and 132 participants completed this study.Following the 12-week treatment,significant improvements in both primary and secondary outcomes were observed in the stationary and individualized treatment groups.No remarkable difference in the primary outcomes between the two groups was observed.However,there was a significant difference in the Traditional Chinese Medicine symptom scores(18±7 vs 15±6;P＜0.05).There were no severe adverse effects.CONCLUSION:Compared with stationary treatment,individualized treatment is more effective at relieving the Traditional Chinese Medicine symptoms and improving vision and fundus lesions at 12 weeks post treatment.
文献关键词：
中图分类号：
作者姓名：
HUO Jian;DUAN Junguo;LIU Lisha;ZHANG Fuwen;ZHU Keyu;SUI Jiaqing;JIAN Wenyuan
作者机构：
Department of Ophthalmology,Chengdu Women's and Children's Central Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu 611731,China;College of Ophthalmology,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China
文献出处：
引用格式：
[1]HUO Jian;DUAN Junguo;LIU Lisha;ZHANG Fuwen;ZHU Keyu;SUI Jiaqing;JIAN Wenyuan-.Evaluation of individualized treatment of nonproliferative diabetic retinopathy:a multicenter,randomized,parallel-controlled study)[J].中医杂志（英文版）,2022(01):90-95
A类：
nonproliferative,Qiming
B类：
Evaluation,individualized,treatment,diabetic,retinopathy,multicenter,randomized,parallel,controlled,study,OBJECTIVE,To,evaluate,differences,efficacy,stationary,patients,NPDR,METHODS,This,was,clinical,trial,Participants,were,into,given,basic,granules,Chinese,herbal,medicines,over,period,therapeutic,formula,also,changed,adjust,changes,presentation,We,conducted,observations,fundus,retinal,exudation,hemorrhage,visual,acuity,Traditional,Medicine,scores,other,indicators,RESULTS,total,participants,completed,this,Following,significant,improvements,both,primary,secondary,outcomes,observed,groups,No,remarkable,between,two,However,there,There,severe,adverse,effects,CONCLUSION,Compared,more,effective,relieving,symptoms,improving,vision,lesions,weeks,post
AB值：
0.445377
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