典型文献
Miniaturized structured illumination microscopy with diffractive optics
文献摘要：
Structured illumination microscopy(SIM)is an advanced microscope system that provides superresolution capability with excellent imaging speed,which has become a practical tool for live-cell imaging.However,the bulky size is blocking the application of SIM in wider study fields and scenarios.Here,we developed a minia-turized SIM(Mini SIM)system that provided periodic illumination using a diffractive optical element(DOE)for the first time.This optimized phase-only DOE generated the two-dimensional sinusoidal illumination by optical Fourier transform with an illuminating objective lens,which substantially simplified and miniaturized the illumination system.We built up a Mini SIM prototype and demonstrated lateral superresolution imaging of fluorescence beads and A549 cell slides.The proposed Mini SIM greatly simplifies the experimental setup and may lead to important applications in bio-imaging.
文献关键词：
中图分类号：
作者姓名：
GUOXUAN LIU;NING XU;HUAIDONG YANG;QIAOFENG TAN;GUOFAN JIN
作者机构：
State Key Laboratory of Precision Measurement Technology and Instruments,Department of Precision Instrument,Tsinghua University Beijing 100084,China
文献出处：
引用格式：
[1]GUOXUAN LIU;NING XU;HUAIDONG YANG;QIAOFENG TAN;GUOFAN JIN-.Miniaturized structured illumination microscopy with diffractive optics)[J].光子学研究（英文）,2022(05):1317-1324
A类：
superresolution,turized
B类：
Miniaturized,structured,illumination,microscopy,diffractive,optics,Structured,SIM,advanced,microscope,system,that,provides,capability,excellent,imaging,speed,which,become,practical,tool,live,However,bulky,size,blocking,wider,study,fields,scenarios,Here,developed,provided,periodic,using,optical,element,DOE,first,This,optimized,phase,only,generated,two,dimensional,sinusoidal,by,Fourier,transform,illuminating,objective,lens,substantially,simplified,miniaturized,We,built,prototype,demonstrated,lateral,fluorescence,beads,A549,slides,proposed,greatly,simplifies,experimental,setup,may,lead,important,applications,bio
AB值：
0.607539
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