典型文献
Evolving paradigms for natural-product drug discovery
文献摘要:
Natural products and their derivatives have remained a reliable source of new pharmaceutical agents in the past 30 years[1].For the future,however,new paradigms are requisite for the more high-profile,sustainable and focused exploration of nature,employing the contemporary technologies to address global disease needs[2].The first of these is to shift from the Western'big pharma'paradigm to one in which the initiatives are responsive to global patient-centered needs.To respond to the clinical urgency,approval systems are needed for a new class of standardized,safe and effective natural medicinal agents.Approval im-plies accessibility and there is a prevalent myth that the registered medicines(phar-maceuticals or traditional medicines)will always be there.That can only occur after the notion of'medicines security'(availability,affordability and a safe and effective product consistency)is adopted by the World Health Organization[2].
文献关键词:
中图分类号:
作者姓名:
Geoffrey A.Cordell
作者机构:
Natural Products Inc.,USA;College of Pharmacy,University of Florida,USA
文献出处:
引用格式:
[1]Geoffrey A.Cordell-.Evolving paradigms for natural-product drug discovery)[J].国家科学评论(英文版),2022(11):5-6
A类:
maceuticals
B类:
Evolving,paradigms,natural,drug,discovery,Natural,products,their,derivatives,have,remained,reliable,source,new,pharmaceutical,agents,past,years,For,future,however,are,requisite,more,high,profile,sustainable,focused,exploration,nature,employing,contemporary,technologies,address,global,disease,needs,first,these,shift,from,big,one,which,initiatives,responsive,patient,centered,To,respond,clinical,urgency,approval,systems,needed,class,standardized,safe,effective,medicinal,Approval,im,plies,accessibility,there,prevalent,myth,that,registered,medicines,traditional,will,always,be,That,can,only,occur,after,notion,security,availability,affordability,consistency,adopted,by,World,Health,Organization
AB值:
0.699159
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