首站-论文投稿智能助手
典型文献
Evolving paradigms for natural-product drug discovery
文献摘要:
Natural products and their derivatives have remained a reliable source of new pharmaceutical agents in the past 30 years[1].For the future,however,new paradigms are requisite for the more high-profile,sustainable and focused exploration of nature,employing the contemporary technologies to address global disease needs[2].The first of these is to shift from the Western'big pharma'paradigm to one in which the initiatives are responsive to global patient-centered needs.To respond to the clinical urgency,approval systems are needed for a new class of standardized,safe and effective natural medicinal agents.Approval im-plies accessibility and there is a prevalent myth that the registered medicines(phar-maceuticals or traditional medicines)will always be there.That can only occur after the notion of'medicines security'(availability,affordability and a safe and effective product consistency)is adopted by the World Health Organization[2].
文献关键词:
作者姓名:
Geoffrey A.Cordell
作者机构:
Natural Products Inc.,USA;College of Pharmacy,University of Florida,USA
引用格式:
[1]Geoffrey A.Cordell-.Evolving paradigms for natural-product drug discovery)[J].国家科学评论(英文版),2022(11):5-6
A类:
maceuticals
B类:
Evolving,paradigms,natural,drug,discovery,Natural,products,their,derivatives,have,remained,reliable,source,new,pharmaceutical,agents,past,years,For,future,however,are,requisite,more,high,profile,sustainable,focused,exploration,nature,employing,contemporary,technologies,address,global,disease,needs,first,these,shift,from,big,one,which,initiatives,responsive,patient,centered,To,respond,clinical,urgency,approval,systems,needed,class,standardized,safe,effective,medicinal,Approval,im,plies,accessibility,there,prevalent,myth,that,registered,medicines,traditional,will,always,be,That,can,only,occur,after,notion,security,availability,affordability,consistency,adopted,by,World,Health,Organization
AB值:
0.699159
相似文献
Massive feature extraction for explaining and foretelling hydroclimatic time series forecastability at the global scale
Georgia Papacharalampous;Hristos Tyralis;Ilias G.Pechlivanidis;Salvatore Grimaldi;Elena Volpi-Department of Engineering,Roma Tre University,Via V.Volterra 62,00146 Rome,Italy;Department of Water Resources and Environmental Engineering,School of Civil Engineering,National Technical University of Athens,Heroon Polytechneiou 5,15780 Zographou,Greece;Hellenic Air Force General Staff,Hellenic Air Force,Mesogion Avenue 227-231,15561 Cholargos,Greece;Swedish Meteorological and Hydrological Institute,60176 Norrk?ping,Sweden;Department for Innovation in Biological,Agro-food and Forest Systems,University of Tuscia,Viterbo,Italy;Department of Mechanical and Aerospace Engineering,Tandon School of Engineering,New York University,Brooklyn,NY,10003,United States
Carbonized waste milk powders as cathodes for stable lithium-sulfur batteries with ultra-large capacity and high initial coulombic efficiency
Rabia Khatoon;Sanam Attique;Rumin Liu;Sajid Rauf;Nasir Ali;Luhong Zhang;Yu-Jia Zeng;Yichuan Guo;Yusuf Valentino Kaneti;Jongbeom Na;Haichao Tang;Hongwen Chen;Yang Tian;Jianguo Lu-State Key Laboratory of Silicon Materials,Key Laboratory for Biomedical Engineering of Ministry of Education,School of Materials Science and Engineering,Zhejiang University,Hangzhou,310027,China;Institute for Composites Science Innovation,School of Materials Science and Engineering,Zhejiang University,Hangzhou,310027,China;Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials,Faculty of Physics and Electronic Science,Hubei University,Wuhan,Hubei,430062,China;State Key Laboratory for Silicon Materials,Key Laboratory of Quantum Technology and Devices,Department of Physics,Zhejiang University,Hangzhou,310027,China;College of Physics and Optoelectronic Engineering,Shenzhen University,Shenzhen,518060,China;International Center for Materials Nanoarchitectonics(WPI-MANA),National Institute for Materials Science(NIMS),1-1 Namiki,Ibaraki,305-0044,Japan;School of Chemical Engineering&Australian Institute for Bioengineering and Nanotechnology(AIBN),The University of Queensland,Brisbane,QLD,4072,Australia
Measuring and evaluating SDG indicators with Big Earth Data
Huadong Guo;Dong Liang;Zhongchang Sun;Fang Chen;Xinyuan Wang;Junsheng Li;Li Zhu;Jinhu Bian;Yanqiang Wei;Lei Huang;Yu Chen;Dailiang Peng;Xiaosong Li;Shanlong Lu;Jie Liu;Zeeshan Shirazi-International Research Center of Big Data for Sustainable Development Goals,Beijing 100094,China;Key Laboratory of Digital Earth Science,Aerospace Information Research Institute,Chinese Academy of Sciences,Beijing 100094,China;University of Chinese Academy of Sciences,Beijing 100049,China;Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China;Institute of Mountain Hazards and Environment,Chinese Academy of Sciences,Chengdu 610041,China;Key Laboratory of Remote Sensing of Gansu Province,Northwest Institute of Eco-Environment and Resources,Chinese Academy of Sciences,Lanzhou 730000,China
Alzheimer's disease:current status and perspective
Wenying Liu;Serge Gauthier;Jianping Jia-Innovation Center for Neurological Disorders and Department of Neurology,Xuanwu Hospital,Capital Medical University,National Clinical Research Center for Geriatric Diseases,Beijing 100053,China;Departments of Neurology and Neurosurgery,and Department of Psychiatry,McGill Centre for Studies in Aging,McGill University,Montreal H4H1R3,Canada;Beijing Key Laboratory of Geriatric Cognitive Disorders,Beijing 100053,China;Clinical Center for Neurodegenerative Disease and Memory Impairment,Capital Medical University,Beijing 100053,China;Center of Alzheimer's Disease,Beijing Institute of Brain Disorders,Collaborative Innovation Center for Brain Disorders,Capital Medical University,Beijing 100053,China;Key Laboratory of Neurodegenerative Diseases,Ministry of Education,Beijing 100053,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。