典型文献
Preparation of Poly(ε-caprolactone)/Poly(ester amide)Electrospun Membranes for Vascular Repair
文献摘要:
With adjustable amphiphilicity and anionic/cationic charge,biodegradability and biocompatibility,amino acid-based poly(ester amide)s(PEAs)have drawn attention in the research of tissue engineered vascular grafts.In this work,L-phenylalanine-based PEAs with or without L-lysine were synthesized through polycondensation,and ultrafine fibrous grafts consisted of PEAs and poly(ε-caprolactone)(PCL)in given mass ratios were further prepared via blend electrospinning.Surface characterizations by Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy confirmed the chemical structure,and the wettability indicated that the prepared PCL/PEAs electrospun membranes exhibited less hydrophobic than PCL.Tensile results showed that the PCL/PEAs membranes possessed suitable mechanical properties,which could meet the requirements of artificial blood vessels.Cell culture and hemolytic tests exhibited that the PCL/PEAs electrospun membranes are biocompatible.In general,the electrospun grafts of PCL/PEAs could be applied for vascular repair.
文献关键词:
中图分类号:
作者姓名:
ZHANG Xiangyu;BAI Shan;ZANG Leilei;CHEN Xiaoqi;YUAN Xiaoyan
作者机构:
School of Materials Science and Engineering,Tianjin Key Laboratory of Composite and Functional Materials,Tianjin University,Tianjin 300350,P.R.China;Institute of Energy Resources,Hebei Academy of Sciences,Shijiazhuang 050081,P.R.China
文献出处:
引用格式:
[1]ZHANG Xiangyu;BAI Shan;ZANG Leilei;CHEN Xiaoqi;YUAN Xiaoyan-.Preparation of Poly(ε-caprolactone)/Poly(ester amide)Electrospun Membranes for Vascular Repair)[J].高等学校化学研究(英文版),2022(04):1111-1117
A类:
amphiphilicity,PEAs
B类:
Preparation,Poly,caprolactone,ester,amide,Electrospun,Membranes,Vascular,Repair,With,adjustable,anionic,cationic,charge,biodegradability,biocompatibility,amino,acid,have,drawn,attention,research,tissue,engineered,vascular,grafts,In,this,work,phenylalanine,without,lysine,were,synthesized,through,polycondensation,ultrafine,fibrous,consisted,PCL,given,mass,ratios,further,prepared,via,blend,electrospinning,Surface,characterizations,by,Fourier,transform,infrared,spectroscopy,ray,photoelectron,confirmed,chemical,structure,wettability,indicated,that,electrospun,membranes,exhibited,less,hydrophobic,than,Tensile,results,showed,possessed,suitable,mechanical,properties,which,could,meet,requirements,artificial,blood,vessels,Cell,culture,hemolytic,tests,biocompatible,general,be,applied,repair
AB值:
0.627404
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