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典型文献
Programmable Oligonucleotide-Peptide Complexes:Synthesis and Applications
文献摘要:
Nucleic acids form biological blueprint and polypeptides assist life activities,both of which are indispensable to organisms.Recently,oligonucleotide-peptide complexes(OPCs)have shown great potential in biomedicine,material chemistry and other fields due to their considerable stability and programmability.It remains a huge challenge to stably and facilely constructing OPCs that also limits the wide applications.This tutorial review first summarizes the synthesis strategies of OPC conjugation and the corresponding characteristics in detail,then gives examples of the applications of OPCs,and finally presents a prospective overview on challenges and future perspectives of OPCs.This review aims to help researchers understand the current situation and challenges in this field,thereby furthering interests in developing novel OPC synthesis techniques.
文献关键词:
作者姓名:
XU Min;ZHOU Baomei;DING Yan;DU Shanshan;SU Mengke;LIU Honglin
作者机构:
China Light Industry Key Laboratory of Meat Microbial Control and Utili-zation,School of Food and Biological Engineering,Hefei University of Technology,Hefei 230009,P.R.China;First Affiliated Hospital of Anhui Medical University,Hefei 230000,P.R.China
引用格式:
[1]XU Min;ZHOU Baomei;DING Yan;DU Shanshan;SU Mengke;LIU Honglin-.Programmable Oligonucleotide-Peptide Complexes:Synthesis and Applications)[J].高等学校化学研究(英文版),2022(04):856-865
A类:
Oligonucleotide,programmability
B类:
Programmable,Peptide,Complexes,Synthesis,Applications,Nucleic,acids,form,biological,blueprint,polypeptides,assist,life,activities,both,which,are,indispensable,organisms,Recently,oligonucleotide,complexes,OPCs,have,shown,great,potential,biomedicine,material,chemistry,other,fields,due,their,considerable,stability,It,remains,huge,stably,facilely,constructing,that,also,limits,wide,applications,This,tutorial,review,first,summarizes,synthesis,strategies,conjugation,corresponding,characteristics,detail,then,gives,examples,finally,presents,prospective,overview,challenges,future,perspectives,aims,help,researchers,understand,current,situation,this,thereby,furthering,interests,developing,novel,techniques
AB值:
0.738349
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