典型文献
A New Chemical Trick to Prevent House from Collapsing by Bacterial Pathogens
文献摘要:
M etazoans often induce cell death as an ultimate strategy to prevent disastrous damage to the body under circumstances when insults,such as infection are impossible to clear.Inflammatory cell death or pyroptosis not only eliminates the replicative niche for the pathogen but also stimulates effective immune protection.A recent study by Shao,Liu and colleagues found that the Shigella flexneri effector OspC3 inactivates an inflammasome by a novel posttranslational modification termed ADP-riboxanation.This finding has greatly expanded the chemical tool box of pathogens in their manipulation of host function,which may be used to probe unrecognized signaling mechanisms.
文献关键词:
中图分类号:
作者姓名:
QIU Jiazhang;LUO Zhao-Qing
作者机构:
State Key Laboratory for Zoonotic Diseases,College of Veterinary Medicine,Jilin University,Changchun 130061,P.R.China;Purdue Institute for Inflammation,Immunology and Infectious Disease and Department of Biological Sciences,Purdue University,West Lafayette,IN,USA
文献出处:
引用格式:
[1]QIU Jiazhang;LUO Zhao-Qing-.A New Chemical Trick to Prevent House from Collapsing by Bacterial Pathogens)[J].高等学校化学研究(英文版),2022(02):478-480
A类:
Trick,Collapsing,etazoans,OspC3,riboxanation
B类:
New,Chemical,Prevent,House,from,by,Bacterial,Pathogens,often,induce,cell,death,ultimate,strategy,prevent,disastrous,damage,body,under,circumstances,when,insults,such,infection,are,impossible,clear,Inflammatory,pyroptosis,not,only,eliminates,replicative,niche,but,also,stimulates,effective,immune,protection,recent,study,Shao,Liu,colleagues,found,that,Shigella,flexneri,effector,inactivates,inflammasome,novel,posttranslational,modification,termed,ADP,This,finding,has,greatly,expanded,chemical,tool,pathogens,their,manipulation,host,function,which,may,used,probe,unrecognized,signaling,mechanisms
AB值:
0.757546
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