典型文献
Chronic p-Citronellol Inhalation Rescues Parvalbumin Expression Loss in Prefrontal Cortex of Chronic Restraint Stress Mice
文献摘要：
Considerable evidence has revealed that essential oils and their main constituents possess anti-depressant and anxiolytic properties.In the current study,we report the effect of β-citronellol,the main component of rose essential oil,on depressive-like and anxiety-like behaviors in chronic restraint stress(CRS)mice.We found that chronic inhalation of β-citronellol for 14 days could increase locomotor activity in the open field test,de-crease the percentage of immobility duration in the forced swimming test,and increase open arms exploration in elevated plus-maze test in CRS mice.Western blot experiment shows that chronic β-citronellol inhalation res-cues parvalbumin(PV)expression loss in the prefrontal cortex(PFC)of CRS mice.Correlation analysis reveals a strong relationship between the PV expression in PFC and the percentage of sucrose preference of the mice.These findings indicate the relationships between the PV gene expression of PFC and the effects ofβ-citronellol inhalation.
文献关键词：
中图分类号：
作者姓名：
ZHUANG Qianqian;ZHUANG Siyue;GONG Yanling;LI Shengtian
作者机构：
Bio-X Institutes;Key Laboratory for the Genetics of Development and Neuropsychiatric Disorders Ministry of Education;Shanghai Key Laboratory of Psychotic Disorders;Brain Science and Technology Research Center,Shanghai Jiao Tong University,Shanghai 200240,China
文献出处：
引用格式：
[1]ZHUANG Qianqian;ZHUANG Siyue;GONG Yanling;LI Shengtian-.Chronic p-Citronellol Inhalation Rescues Parvalbumin Expression Loss in Prefrontal Cortex of Chronic Restraint Stress Mice)[J].上海交通大学学报（英文版）,2022(04):512-520
A类：
Citronellol,Rescues,Parvalbumin,anxiolytic,citronellol
B类：
Chronic,Inhalation,Expression,Loss,Prefrontal,Cortex,Restraint,Stress,Mice,Considerable,evidence,has,revealed,that,essential,oils,their,main,constituents,possess,anti,depressant,properties,current,study,report,component,depressive,like,anxiety,behaviors,chronic,restraint,stress,CRS,mice,found,inhalation,days,could,increase,locomotor,activity,open,field,test,percentage,immobility,duration,forced,swimming,arms,exploration,elevated,plus,maze,blot,experiment,shows,parvalbumin,PV,expression,loss,prefrontal,cortex,PFC,Correlation,analysis,reveals,strong,between,sucrose,preference,These,findings,indicate,relationships,gene,effects
AB值：
0.545818
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
