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典型文献
Multi-omics Analyses Provide Insight into the Biosynthesis Pathways of Fucoxanthin in Isochrysis galbana
文献摘要:
Isochrysis galbana is considered an ideal bait for functional foods and nutraceuticals of humans because of its high fucoxanthin(Fx)content.However,multi-omics analysis of the regula-tory networks for Fx biosynthesis in I.galbana has not been reported.In this study,we report a high-quality genome assembly of I.galbana LG007,which has a genome size of 92.73 Mb,with a contig N50 of 6.99 Mb and 14,900 protein-coding genes.Phylogenetic analysis confirmed the monophyly of Haptophyta,with I.galbana sister to Emiliania huxleyi and Chrysochromulina tobinii.Evolutionary analysis revealed an estimated divergence time between I.galbana and E.huxleyi of~133 million years ago.Gene family analysis indicated that lipid metabolism-related genes exhibited significant expansion,including IgPLMT,IgOAR1,and IgDEGS1.Metabolome analysis showed that the content of carotenoids in I.galbana cultured under green light for 7 days was higher than that under white light,and β-carotene was the main carotenoid,accounting for 79.09%of the total carotenoids.Comprehensive multi-omics analysis revealed that the content of β-carotene,antheraxanthin,zeaxanthin,and Fx was increased by green light induction,which was significantly correlated with the expression of IgMYB98,IgZDS,IgPDS,IgLHCX2,IgZEP,IgLCYb,and IgNSY.These findings contribute to the understanding of Fx biosynthesis and its regulation,pro-viding a valuable reference for food and pharmaceutical applications.
文献关键词:
作者姓名:
Duo Chen;Xue Yuan;Xuehai Zheng;Jingping Fang;Gang Lin;Rongmao Li;Jiannan Chen;Wenjin He;Zhen Huang;Wenfang Fan;Limin Liang;Chentao Lin;Jinmao Zhu;Youqiang Chen;Ting Xue
作者机构:
The Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Products of the State Oceanic Administration,Center of Engineering Technology Research for Microalga Germplasm Improvement of Fujian,Fujian Key Laboratory of Special Marine Bioresource Sustainable Utilization,Fujian Key Laboratory of Developmental and Neural Biology,Southern Institute of Oceanography,College of Life Sciences,Fujian Normal University,Fuzhou 350117,China;Fujian Fishery Resources Monitoring Center,Fuzhou 350003,China
引用格式:
[1]Duo Chen;Xue Yuan;Xuehai Zheng;Jingping Fang;Gang Lin;Rongmao Li;Jiannan Chen;Wenjin He;Zhen Huang;Wenfang Fan;Limin Liang;Chentao Lin;Jinmao Zhu;Youqiang Chen;Ting Xue-.Multi-omics Analyses Provide Insight into the Biosynthesis Pathways of Fucoxanthin in Isochrysis galbana)[J].基因组蛋白质组与生物信息学报(英文版),2022(06):1138-1153
A类:
Provide,Fucoxanthin,nutraceuticals,LG007,Emiliania,huxleyi,Chrysochromulina,tobinii,IgPLMT,IgOAR1,IgDEGS1,antheraxanthin,IgMYB98,IgZDS,IgPDS,IgLHCX2,IgZEP,IgLCYb,IgNSY
B类:
Multi,omics,Analyses,Insight,into,Biosynthesis,Pathways,Isochrysis,galbana,considered,ideal,bait,functional,foods,humans,because,its,fucoxanthin,Fx,content,However,multi,analysis,tory,networks,biosynthesis,has,not,been,reported,this,study,quality,genome,assembly,which,size,Mb,contig,N50,protein,coding,genes,Phylogenetic,confirmed,monophyly,Haptophyta,sister,Evolutionary,revealed,estimated,divergence,between,million,years,ago,Gene,family,indicated,that,lipid,metabolism,exhibited,expansion,including,Metabolome,showed,carotenoids,cultured,green,light,days,was,higher,than,white,carotene,main,accounting,total,Comprehensive,zeaxanthin,increased,by,induction,significantly,correlated,expression,These,findings,contribute,understanding,regulation,viding,valuable,reference,pharmaceutical,applications
AB值:
0.471447
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