典型文献
Biological functions and diagnostic implications of microRNAs in Mycobacterium tuberculosis infection
文献摘要：
MicroRNAs (miRNAs), small non-coding RNAs, play important roles in regulating host defense against pathogenic infections. This review provides information on the role of miRNAs in the antimycobacterial immune response and summarizes their possible diagnostic utility. It was compiled using scientific literature retrieved from such databases as PubMed, Scopus, ScienceDirect, Google Scholar, and PubMed Central. Relevant articles published in the English language until December 2020 were taken into consideration. It has been revealed that specific host miRNAs induced by Mycobacterium tuberculosis can target diverse factors and pathways in immune signaling to ensure longer pathogen survival inside the phagocytes. The potential use of miRNAs in tuberculosis diagnosis or therapeutic strategies has been attracting increasing attention in recent years. However, despite considerable efforts devoted to miRNA profiling, further studies are needed to elucidate the full potential of miRNAs as novel tuberculosis biomarkers or therapeutic targets.
文献关键词：
中图分类号：
作者姓名：
Godkowicz Magdalena;Druszczynska Magdalena
作者机构：
Department of Immunology and Infectious Biology,Institute of Microbiology,Biotechnology and Immunology,Faculty of Biology and Environmental Protection,University of Lodz,Banacha 12/16,90-237 Lodz,Poland;The Bio-Med-Chem Doctoral School of the University of Lodz and Lodz Institutes of the Polish Academy of Sciences,Lodz,Poland
文献出处：
引用格式：
[1]Godkowicz Magdalena;Druszczynska Magdalena-.Biological functions and diagnostic implications of microRNAs in Mycobacterium tuberculosis infection)[J].亚太热带生物医学杂志（英文版）,2022(01):1-8
A类：
antimycobacterial
B类：
Biological,functions,diagnostic,implications,microRNAs,Mycobacterium,tuberculosis,MicroRNAs,miRNAs,small,coding,play,important,roles,regulating,host,defense,against,pathogenic,infections,This,review,provides,information,immune,response,summarizes,their,possible,utility,It,was,compiled,using,scientific,literature,retrieved,from,such,databases,Scopus,ScienceDirect,Google,Scholar,Central,Relevant,articles,published,English,language,until,December,were,taken,into,consideration,has,been,revealed,that,specific,induced,by,can,diverse,factors,pathways,signaling,ensure,longer,survival,inside,phagocytes,potential,use,diagnosis,therapeutic,strategies,attracting,increasing,attention,recent,years,However,despite,considerable,efforts,devoted,profiling,further,studies,are,needed,elucidate,full,novel,biomarkers,targets
AB值：
0.711659
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