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典型文献
Neuroimaging perspective in targeted treatment for type 2 diabetes melitus and sleep disorders
文献摘要:
Type 2 diabetes mellitus (T2DM) and sleep disorders (SD) have become important and costly health issues world-wide, particularly in China. Both are common diseases related to brain functional and structural abnormalities involving the hypothalamic-pituitary-adrenal (HPA) axis. The brains of individuals who suffer from both diseases simultaneously might be different compared to healthy individuals. This review assessed current neuroimaging findings to develop alternative targeted treatments for T2DM and SD. Relevant articles published between January 2002 and September 2021 were searched in PubMed and Web of Science databases. Generalized treatment methods for T2DM include dietary/weight-loss management, metformin or a combination of two non-insulin drugs, and melatonin for SD, though alternative therapies including electroacupuncture (EA) have been utilized in treating both of these diseases separately because they are convenient, affordable, and safe. Standard and alternative treatments for T2DM were somehow effective in treating SD. Neuroimaging studies of these disorders can achieve higher treatment efficacy by targeting brain areas, such as the hypothalamus (HYP), as visualized via diffusion tensor imaging (DTI), and functional magnetic resonance imaging (fMRI). DTI and fMRI can map the human brain and are utilized in many experiments. Thus, we propose that neuroimaging studies could be used in treatment of SD in T2DM.
文献关键词:
Neuroimaging;Diabetes mellitus;Sleep disorders;Alternative medicine;Electroacupuncture;Hypothalamic-pituitary-adrenal axis
作者姓名:
von Deneen Karen M.;Garstka Malgorzata A.
作者机构:
Center for Brain Imaging, School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710126, China;International Joint Research Center for Advanced Medical Imaging and Intelligent Diagnosis and Treatment & Xi’an Key Laboratory of Intelligent Sensing and Regulation of trans-Scale Life Information, School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710126, China;Core Research Laboratory, Department of Endocrinology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710004, China;Department of Tumor and Immunology, Precision Medical Institute, Western China Science and Technology Innovation Port, School of Medicine, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710004, China
引用格式:
[1]von Deneen Karen M.;Garstka Malgorzata A.-.Neuroimaging perspective in targeted treatment for type 2 diabetes melitus and sleep disorders)[J].智慧医学(英文),2022(04):209-220
A类:
melitus
B类:
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AB值:
0.63901
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