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典型文献
Phytochemical analysis and inhibitory effects of Calligonum polygonoides on pancreatic a-amylase and β-glucosidase enzymes
文献摘要:
OBJECTIVES:To estimate the existence of phyto-chemicals and then to determine the antidiabetic activity against a-amylase and 3-glucosidase inhibition in vitro.METHODS:The study was carried out by following standard procedures.RESULTS:Phytochemicals analysis indicated the presence of different phytochemicals.The total phenolic content was 6.055 mg GAE/g and the total flavonoid content was 5.706 mg RU/g in the plant extract.The total saponins,alkaloids,and tannins contents were(0.044%),(2.88%)and(2.862 nm)respectively.a-amylase inhibition activity of Calligonum polygonoides(CP)extract was 70%with IC50 of 610 pg/mL and that of p-gluco-sidase inhibition activity was 65%with IC50 of 640 pg/mL.CONCLUSION:The findings reported for the first time the antidiabetes-promoting effects of an extract of CP in vitro,thus validating their promising anti-diabetes potential.
文献关键词:
作者姓名:
Mushtaq Ahmed;Naila Sher;Nadia Mushtaq;Rahmat Ali Khan
作者机构:
Department of Biotechnology,Faculty of Biological Sciences,University of Science&Technology,Bannu 28100,KPK-Pakistan;Department of Botany,Faculty of Biological Sciences,University of Science&Technology,Bannu 28100,KPK-Pakistan
引用格式:
[1]Mushtaq Ahmed;Naila Sher;Nadia Mushtaq;Rahmat Ali Khan-.Phytochemical analysis and inhibitory effects of Calligonum polygonoides on pancreatic a-amylase and β-glucosidase enzymes)[J].中医杂志(英文版),2022(03):426-431
A类:
Calligonum,polygonoides,OBJECTIVES,gluco,sidase,antidiabetes
B类:
analysis,inhibitory,effects,pancreatic,amylase,glucosidase,enzymes,To,estimate,existence,then,determine,antidiabetic,activity,against,inhibition,vitro,METHODS,study,was,carried,out,by,following,standard,procedures,RESULTS,Phytochemicals,indicated,presence,different,phytochemicals,total,phenolic,GAE,flavonoid,RU,plant,extract,saponins,alkaloids,tannins,contents,were,respectively,CP,IC50,pg,that,CONCLUSION,findings,reported,first,promoting,thus,validating,their,promising,potential
AB值:
0.503951
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