典型文献
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul
文献摘要：
Objective: To examine the effect of the COVID-19 virus, especially the Omicron variant, on hematological parameters of hospitalized pediatric patients during the COVID-19 pandemic.Methods: Medical records of pediatric COVID-19 patients hospitalized at Kartal Dr. Lütfi K?rdar City Hospital in Istanbul, Turkey, between March 2020 and May 2022 were retrospectively reviewed to analyze data regarding demographics, SARS-CoV-2 infection polymerase chain reaction (PCR) test results, reverse-transcriptase (RT)-PCR for other respiratory agents, duration of hospital stay, and hematological and biochemical laboratory findings. Results: Out of 467 children with a confirmed diagnosis of SARS-CoV-2 infection, 94 (20.1％) had Omicron infection and 373 (79.9％) were infected with other variants; the Omicron group had younger patients than the remaining samples (P<0.001). The most frequent clinical symptoms in all children were cough (53.5％) and fever (32.3％), followed by vomiting (20.8％). Lung involvement in the Omicron group (10.6％) was significantly lower than in the remaining samples (29.8％) (P<0.001). Hemoglobin and lymphocyte levels were lower in the Omicron-infected group (both P<0.001), while prothrombin time, activated partial thromboplastin time, international normalized ratio, and D-dimer levels were significantly higher in this group (P<0.001, P<0.001, P<0.001, and P=0.023, respectively). In terms of lung involvement, those with lung involvement were significantly older (P<0.001). Conclusions: Although lung involvement was less common with Omicron infection, this group had greater hematological system involvement, such as anemia, lymphopenia, D-dimer elevation, and coagulation disorders.
文献关键词：
中图分类号：
作者姓名：
Berkin Berk Akbeyaz;Ayşe Karaaslan;CerenÇetin;Mehmet Tolga Köle;Zeynep Altaş;Yasemin Akın
作者机构：
Department of Pediatrics,University of Health Sciences,Kartal Dr.Lütfi K?rdar City Hospital,Pediatric Hematology and Oncology Istanbul,Turkey;Department of Pediatric Infectious Diseases,University of Health Sciences,Kartal Dr.Lütfi K?rdar City Hospital,Istanbul,Turkey;Department of Pediatrics,University of Health Sciences,Kartal Dr.Lütfi K?rdar City Hospital,Istanbul,Turkey;Department of Public Health,Marmara University,Istanbul,Turkey
文献出处：
引用格式：
[1]Berkin Berk Akbeyaz;Ayşe Karaaslan;CerenÇetin;Mehmet Tolga Köle;Zeynep Altaş;Yasemin Akın-.Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul)[J].亚太热带医药杂志（英文版）,2022(12):551-557
A类：
Istanbul,Kartal,tfi,rdar,lymphopenia
B类：
Hematological,profile,infected,children,before,after,spread,Omicron,Objective,To,examine,effect,virus,especially,hematological,parameters,hospitalized,pediatric,patients,during,pandemic,Methods,Medical,records,Dr,City,Hospital,Turkey,between,March,May,were,retrospectively,reviewed,analyze,data,regarding,demographics,SARS,CoV,infection,polymerase,chain,reaction,test,results,reverse,transcriptase,other,respiratory,agents,duration,stay,biochemical,laboratory,findings,Results,Out,confirmed,diagnosis,had,variants,group,younger,than,remaining,samples,most,frequent,clinical,symptoms,cough,fever,followed,by,vomiting,Lung,involvement,was,significantly,lower,Hemoglobin,lymphocyte,levels,both,while,prothrombin,activated,partial,thromboplastin,international,normalized,dimer,higher,this,respectively,In,terms,lung,those,older,Conclusions,Although,less,common,greater,system,such,anemia,elevation,coagulation,disorders
AB值：
0.554426
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