典型文献
Non-albicans candidemia in cancer patients as an increasing health problem: A comprehensive review and meta-analysis
文献摘要：
Objective: To evaluate the prevalence of Candida species in cancer patients with candidemia around the world, and to identify related risk factors and their antifungal resistance, with an emphasis on non-albicans Candida species (NACs).Methods: The published papers related to the subject were systematically searched in databases of MEDLINE (including PubMed), Web of Science, Scopus, Science Direct, and Google Scholar between the 1st January 2000 and 21st April 2021. Results: Among the 4546 records, 69 studies met the inclusion criteria. The pooled prevalence of NACs in cancer patients with candidemia was 62％ (95％ CI 58％-67％; I2=94.85％, P=0.00). Based on type of cancer, the pooled prevalence of NACs in hematologic and solid cancer patients were 68％ (95％ CI 65％-70％) and 52％ (95％ CI 49％-54％), respectively. Among NACs, Candida (C.) parapsilosis was the most frequently isolated organism followed by C. tropicalis and C. glabrata. In addition, the therapeutic usage of antibiotics was found as the most common risk factor, accounting for 85％ (95％ CI 81％-89％) and central venous catheter accounting for 69％ (95％ CI 62％-77％). Conclusions: The incidence of Candida bloodstream infections among cancer patients is a growing concern, especially when the etiologic agents of candidemia tend to shift towards NACs.
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中图分类号：
作者姓名：
Aynaz Ghojoghi;Maryam Erfaninejad;Ehsan Ahmadpour;Eisa Nazar;Aleksandra Barac;Mahnaz Fatahinia
作者机构：
Department of Medical Mycology,School of Medicine,Ahvaz Jundishapur University of Medical Sciences,Ahvaz,Iran;Infectious and Tropical Diseases Research Center,Tabriz University of Medical Sciences,Tabriz,Iran;Department of Biostatistics,School of Health,Mashhad University of Medical Sciences,Mashhad,Iran;Clinic for Infectious and Tropical Diseases,Clinical Centre of Serbia,Belgrade,Serbia
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引用格式：
[1]Aynaz Ghojoghi;Maryam Erfaninejad;Ehsan Ahmadpour;Eisa Nazar;Aleksandra Barac;Mahnaz Fatahinia-.Non-albicans candidemia in cancer patients as an increasing health problem: A comprehensive review and meta-analysis)[J].亚太热带医药杂志（英文版）,2022(09):387-399,中插1-中插12
A类：
candidemia,parapsilosis,glabrata
B类：
Non,albicans,cancer,patients,increasing,health,problem,comprehensive,review,meta,analysis,Objective,To,evaluate,prevalence,Candida,species,around,world,identify,related,risk,factors,their,antifungal,resistance,emphasis,NACs,Methods,published,papers,subject,were,systematically,searched,databases,MEDLINE,including,Scopus,Direct,Google,Scholar,between,January,21st,April,Results,Among,records,studies,inclusion,criteria,pooled,was,I2,Based,type,hematologic,solid,respectively,most,frequently,isolated,organism,followed,by,tropicalis,In,addition,therapeutic,usage,antibiotics,found,common,accounting,central,venous,catheter,Conclusions,incidence,bloodstream,infections,among,growing,concern,especially,when,etiologic,agents,tend,shift,towards
AB值：
0.549913
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