典型文献
Plant pan-genomics:recent advances,new challenges,and roads ahead
文献摘要：
Pan-genomics can encompass most of the genetic diversity of a species or population and has proved to be a powerful tool for studying genomic evolution and the origin and domestication of species,and for providing information for plant improvement.Plant genomics has greatly progressed because of im-provements in sequencing technologies and the rapid reduction of sequencing costs.Nevertheless,pan-genomics still presents many challenges,including computationally intensive assembly methods,high costs with large numbers of samples,ineffective integration of big data,and difficulty in applying it to downstream multi-omics analysis and breeding research.In this review,we summarize the definition and recent achievements of plant pan-genomics,computational technologies used for pan-genome con-struction,and the applications of pan-genomes in plant genomics and molecular breeding.We also discuss challenges and perspectives for future pan-genomics studies and provide a detailed pipeline for sample selection,genome assembly and annotation,structural variation identification,and construction and application of graph-based pan-genomes.The aim is to provide important guidance for plant pan-genome research and a better understanding of the genetic basis of genome evolution,crop domestication,and phenotypic diversity for future studies.
文献关键词：
中图分类号：
作者姓名：
Wei Li;Jianan Liu;Hongyu Zhang;Ze Liu;Yu Wang;Longsheng Xing;Qiang He;Huilong Du
作者机构：
School of Life Sciences,Institute of Life Sciences and Green Development,Hebei University,Baoding,Hebei 071000,China
文献出处：
引用格式：
[1]Wei Li;Jianan Liu;Hongyu Zhang;Ze Liu;Yu Wang;Longsheng Xing;Qiang He;Huilong Du-.Plant pan-genomics:recent advances,new challenges,and roads ahead)[J].遗传学报,2022(09):833-846
A类：
provements
B类：
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AB值：
0.537399
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