典型文献
Transmissibility of tuberculosis among students and non-students: an occupational-specific mathematical modelling
文献摘要：
Background::Recently, despite the steady decline in the tuberculosis (TB) epidemic globally, school TB outbreaks have been frequently reported in China. This study aimed to quantify the transmissibility of
Mycobacterium tuberculosis (MTB) among students and non-students using a mathematical model to determine characteristics of TB transmission.
Methods::We constructed a dataset of reported TB cases from four regions (Jilin Province, Xiamen City, Chuxiong Prefecture, and Wuhan City) in China from 2005 to 2019. We classified the population and the reported cases under student and non-student groups, and developed two mathematical models [nonseasonal model (Model A) and seasonal model (Model B)] based on the natural history and transmission features of TB. The effective reproduction number (
R
eff) of TB between groups were calculated using the collected data.
Results::During the study period, data on 456,423 TB cases were collected from four regions: students accounted for 6.1% of cases. The goodness-of-fit analysis showed that Model A had a better fitting effect (
P < 0.001). The average
R
eff of TB estimated from Model A was 1.68 [interquartile range (IQR): 1.20–1.96] in Chuxiong Prefecture, 1.67 (IQR: 1.40–1.93) in Xiamen City, 1.75 (IQR: 1.37–2.02) in Jilin Province, and 1.79 (IQR: 1.56–2.02) in Wuhan City. The average
R
eff of TB in the non-student population was 23.30 times (1.65/0.07) higher than that in the student population.
Conclusions::The transmissibility of MTB remains high in the non-student population of the areas studied, which is still dominant in the spread of TB. TB transmissibility from the non-student-to-student-population had a strong influence on students. Specific interventions, such as TB screening, should be applied rigorously to control and to prevent TB transmission among students.
文献关键词：
Tuberculosis;Transmission;Compartmental model;Occupational-specific dynamics;Student;Non-student;China
中图分类号：
作者姓名：
Chen Qiuping;Yu Shanshan;Rui Jia;Guo Yichao;Yang Shiting;Abudurusuli Guzainuer;Yang Zimei;Liu Chan;Luo Li;Wang Mingzhai;Lei Zhao;Zhao Qinglong;Gavotte Laurent;Niu Yan;Frutos Roger;Chen Tianmu
作者机构：
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian, People’s Republic of China;CIRAD, URM 17, Intertryp, Montpellier, France;Université de Montpellier, Montpellier, France;Xiamen Center for Disease Control and Prevention, Xiamen, Fujian, People’s Republic of China;Jilin Provincial Center for Disease Control and Prevention, Changchun, Jilin, People’s Republic of China;Espace-Dev, Université de Montpellier, Montpellier, France;Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing, China
文献出处：
引用格式：
[1]Chen Qiuping;Yu Shanshan;Rui Jia;Guo Yichao;Yang Shiting;Abudurusuli Guzainuer;Yang Zimei;Liu Chan;Luo Li;Wang Mingzhai;Lei Zhao;Zhao Qinglong;Gavotte Laurent;Niu Yan;Frutos Roger;Chen Tianmu-.Transmissibility of tuberculosis among students and non-students: an occupational-specific mathematical modelling)[J].贫困所致传染病（英文）,2022(06):5-26
A类：
Transmissibility,Chuxiong,nonseasonal,Compartmental
B类：
tuberculosis,among,students,occupational,specific,mathematical,modelling,Background,Recently,despite,steady,decline,epidemic,globally,school,outbreaks,have,been,frequently,reported,China,This,study,aimed,quantify,transmissibility,Mycobacterium,MTB,using,determine,characteristics,transmission,Methods,We,constructed,dataset,cases,from,four,regions,Jilin,Province,Xiamen,City,Prefecture,Wuhan,classified,population,under,groups,developed,two,models,Model,natural,history,features,effective,reproduction,number,R
,between,were,calculated,collected,Results,During,period,accounted,goodness,analysis,showed,that,had,better,fitting,average,estimated,was,interquartile,range,IQR,times,higher,than,Conclusions,remains,areas,studied,which,still,dominant,spread,strong,influence,Specific,interventions,such,screening,should,applied,rigorously,control,prevent,Tuberculosis,Transmission,Occupational,dynamics,Student,Non
AB值：
0.440941
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
