典型文献
Crown ether-thiourea conjugates as ion transporters
文献摘要：
Na+,Cl-and K+are the most abundant electrolytes present in biological fluids that are essential to the regulation of pH homeostasis,membrane potential and cell volume in living organisms.Herein,we report synthetic crown ether-thiourea conjugates as a cation/anion symporter,which can transport both Na+and Cl-across lipid bilayers with relatively high transport activity.Surprisingly,the ion transport activities were diminished when high concentrations of K+ions were present outside the vesicles.This unusual behavior resulted from the strong affinity of the transporters for K+ions,which led to predominant partitioning of the transporters as the K+complexes in the aqueous phase preventing the transporter incorporation into the membrane.Synthetic membrane transporters with Na+,Cl-and K+transport capabilities may have potential biological and medicinal applications.
文献关键词：
中图分类号：
作者姓名：
Zhixing Zhao;Bailing Tang;Xiaosheng Yan;Xin Wu;Zhao Li;Philip A.Gale;Yun-Bao Jiang
作者机构：
Department of Chemistry,College of Chemistry and Chemical Engineering,The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation,iChEM,Xiamen University,Xiamen 361005,China;School of Chemistry(F11),The University of Sydney,Sydney,NSW 2006,Australia;The University of Sydney Nano Institute(Sydney Nano),The University of Sydney,Sydney,NSW 2006,Australia
文献出处：
引用格式：
[1]Zhixing Zhao;Bailing Tang;Xiaosheng Yan;Xin Wu;Zhao Li;Philip A.Gale;Yun-Bao Jiang-.Crown ether-thiourea conjugates as ion transporters)[J].化学科学与工程前沿,2022(01):81-91
A类：
K+are,K+complexes,K+transport
B类：
Crown,ether,thiourea,conjugates,transporters,Cl,most,abundant,electrolytes,present,biological,fluids,that,essential,regulation,homeostasis,membrane,potential,cell,volume,living,organisms,Herein,report,synthetic,crown,anion,symporter,which,can,both,Na+and,across,lipid,bilayers,relatively,high,activity,Surprisingly,activities,were,diminished,when,concentrations,K+ions,outside,vesicles,This,unusual,behavior,resulted,from,strong,affinity,led,predominant,partitioning,aqueous,phase,preventing,incorporation,into,Synthetic,capabilities,may,have,medicinal,applications
AB值：
0.595217
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