Diabetes,one of the most serious metabolism diseases,has continually plagued human beings so that timely monitored blood glucose level is very necessary.Gold nanoparticles(AuNPs)have been consid-ered as potential substitutes for non-enzymatic sensors,due to their unusual physicochemical property and efficient catalytic activity.Herein,we prepared a facial platform for AuNPs to maintain good disper-sity and inherent physicochemical property.In this special platform(SH-nGO-PEG-RhB),nanographene oxide(nGO)was employed as an ideal base,which provided adequate carboxyls for conjugating with poly(ethylene glycol)(PEG),and enough epoxy groups for thiol active site.A functional dye(rhodamine B)with preferable fluorescence properties was also introduced into this platform.AuNPs were then aptly in situ grown on the platform via reduction of HAuCl4 under mild conditions,providing AuNPs@SH-nGO-PEG-RhB.The nanocomposite was cast on a glassy carbon electrode(GCE)conveniently,yielding GCE/AuNPs@SH-nGO-PEG-RhB.Reasonably,as shown by cyclic voltammetry(CV)and ready-state amper-ometry,GCE/AuNPs@SH-nGO-PEG-RhB was capable of electrochemical determination of glucose so as to provide an efficient sensor for glucose determination with dye tracer.

Department of Stomatology,Shanghai Xuhui District Dental Center,500 Fenglin Road,Shanghai 200032,China;Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules,Center for Excellence in Molecular Synthesis,Chinese Academy of Sciences,Shanghai Institute of Organic Chemistry,University of Chinese Academy of Sciences,Shanghai 200032,China

[1]Wenhao Qian;Tao Song;Mao Ye;Xiaoyu Huang;Yongjun Li;Bingjie Hao-.Functionalized nanographene oxide/PEG/rhodamine B/gold nanocomposite for electrochemical determination of glucose)[J].材料科学技术（英文版）,2022(27):141-147

nanographene,nGO,carboxyls,aptly,Reasonably,amper

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