典型文献
3D Biocompatible Polyester Blend Scaffolds Containing Degradable Calcium Citrate for Bone Tissue Engineering
文献摘要：
In this study,a novel porous 3D composite scaffold based on the biodegradable Poly(e-caprolactone)(PCL),Polylactide Acid(PLA)and Calcium Citrate(CC)was developed via polymer blends and thermal-induced phase separation.The chemical structure,crystalline structure and micromorphology as well as mechanical strength of the scaffolds were characterized by Fourier Transform Infrared Spectroscopy(FTIR),X-ray Diffraction(XRD),Scanning Electron Microscope(SEM)and ten-sile tests.The results show that the obtained composite scaffold present a suitable bone-like porous structure and sufficient mechanical strength.Furthermore,the release of calcium ions in Simulated Body Fluid(SBF)indicates that the composite material can provide a stable calcium-ion environment and maintain a constant pH value during the soaking process.The cell proliferation results from CCK-8 and light microscopy show that MG63 cells exhibit excellent adhesion and proliferation on the stent.At the same time,animal implantation histology confirms that the composite scaffolds have good biocompatibility in vivo.The scaffold material has greatly potential application value in the field of bone tissue engineering.
文献关键词：
中图分类号：
作者姓名：
Yifei Xiao;Li Wang;Kun Luo;Yanan Yang;Peicong Zhang;Junfeng Li
作者机构：
College of Materials,Chemistry and Chemical Engineering,Chengdu University of Technology,Chengdu 610059,Sichuan,People's Republic of China
文献出处：
引用格式：
[1]Yifei Xiao;Li Wang;Kun Luo;Yanan Yang;Peicong Zhang;Junfeng Li-.3D Biocompatible Polyester Blend Scaffolds Containing Degradable Calcium Citrate for Bone Tissue Engineering)[J].仿生工程学报（英文版）,2022(02):497-506
A类：
Polylactide
B类：
Biocompatible,Polyester,Blend,Scaffolds,Containing,Degradable,Calcium,Citrate,Bone,Tissue,Engineering,this,study,novel,porous,composite,biodegradable,caprolactone,PCL,Acid,PLA,was,developed,via,polymer,blends,thermal,induced,phase,separation,chemical,structure,crystalline,micromorphology,well,mechanical,strength,scaffolds,were,characterized,by,Fourier,Transform,Infrared,Spectroscopy,FTIR,ray,Diffraction,Scanning,Electron,Microscope,sile,tests,results,show,that,obtained,present,suitable,bone,like,sufficient,Furthermore,release,calcium,ions,Simulated,Body,Fluid,SBF,indicates,material,provide,stable,environment,maintain,constant,value,during,soaking,process,proliferation,from,CCK,light,microscopy,MG63,cells,exhibit,excellent,adhesion,stent,At,same,animal,implantation,histology,confirms,have,good,biocompatibility,vivo,greatly,potential,application,field,tissue,engineering
AB值：
0.689243
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
