典型文献
Simulation and prediction of membrane fusion dynamics
文献摘要：
Membrane fusion is an important process by which biological membranes perform their life activities.Simulations show that the membrane fusion process happens mainly through three pathways,where the Stalk-Pore hypothesis,in which two membranes come into close contact to form a stalk to a hemifu-sion intermediate,and then the fusion pore opens to achieve completely fusion,is widely accepted,and there exist two free energy barriers that break the current structural steady state for lipid rearrange-ment.Factors of lipid composition,mechanical environment,protein and ion have regulatory roles in the membrane fusion process by effecting membrane curvature structurally and the free energy barriers from energetic perspective.Meanwhile,many theoretical models,represented by the Helfrich model,have been proposed to predict the membrane fusion process.In this paper,we review the research process of membrane fusion and mainly introduce the dynamics of membrane fusion,regulation factors and typical theoretical models.
文献关键词：
中图分类号：
作者姓名：
Zhi Zheng;Shouqin Lü;Mian Long
作者机构：
Center of Biomechanics and Bioengineering Key Laboratory of Microgravity(National Microgravity Laboratory),Beijing Key Laboratory of Engineered Construction and Mechanobiology,and CAS Center for Excellence in Complex System Mechanics,Institute of Mechanics,Chinese Academy of Sciences,Beijing 100190,China;School of Engineering Science,University of Chinese Academy of Sciences,Beijing 100049,China
文献出处：
引用格式：
[1]Zhi Zheng;Shouqin Lü;Mian Long-.Simulation and prediction of membrane fusion dynamics)[J].力学快报（英文）,2022(01):49-55
A类：
Stalk,hemifu,Helfrich
B类：
prediction,fusion,dynamics,Membrane,important,process,by,which,biological,membranes,perform,their,life,activities,Simulations,show,that,happens,mainly,through,three,pathways,where,Pore,hypothesis,two,come,into,close,contact,stalk,intermediate,then,pore,opens,achieve,completely,widely,accepted,there,exist,free,energy,barriers,break,current,steady,state,lipid,rearrange,Factors,composition,mechanical,environment,protein,have,regulatory,roles,effecting,curvature,structurally,from,energetic,perspective,Meanwhile,many,theoretical,models,represented,been,proposed,In,this,paper,we,review,research,introduce,regulation,factors,typical
AB值：
0.582309
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