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典型文献
In Vitro Study on the Repair Effect of Fibronectin Lyophilized Powder
文献摘要:
Fibronectin has a good repair effect on skin, but its practical application is limited by its easy degradation and difficult preservation. Freeze-drying technology can extend the shelf life of biological products, but may cause damage to some of their biological activities. Therefore, it is necessary to conduct comprehensive and scientific testing of fibronectin lyophilized powder prepared by freeze-drying technology to evaluate its actual efficacy. In this study, by means of in vitro cell experiment, zebrafish animal model experiment and the experiment on the human skin, the safety of fibronectin lyophilized powder prepared by the new formula and the actual effcacy of skin repair were preliminarily and multidimensionally evaluated, so as to provide reference and basis for further research, human clinical trial and application. The results showed that fibronectin lyophilized powder prepared by the new formula had low cytotoxicity, significant ability of promoting cell migration and proliferation, and had stronger skin repair effect. The new Fibronectin lyophilized powder has the characteristics of good safety and strong skin repair effect, which shows that it has good development prospects. These results provide a new strategy for the development of skin repair products.
文献关键词:
作者姓名:
Xin Jianxiong;Chen Jun;Qiu Xiao;fengLiu Zhong
作者机构:
Nox Bellcow Cosmetics Co.,Ltd.,Zhongshan,China;National Engineering Research Center of Genetic Medicine,College of Life Science and Technology,Jinan University,China
引用格式:
[1]Xin Jianxiong;Chen Jun;Qiu Xiao;fengLiu Zhong-.In Vitro Study on the Repair Effect of Fibronectin Lyophilized Powder)[J].日用化学品科学(英文),2022(04):56-62
A类:
Lyophilized,effcacy
B类:
In,Vitro,Study,Repair,Effect,Fibronectin,Powder,has,good,repair,effect,skin,but,its,practical,application,limited,by,easy,degradation,difficult,preservation,Freeze,drying,technology,extend,shelf,biological,products,may,cause,damage,some,their,activities,Therefore,necessary,conduct,comprehensive,scientific,testing,fibronectin,lyophilized,powder,prepared,freeze,actual,efficacy,this,study,means,vitro,cell,experiment,zebrafish,animal,model,human,safety,new,formula,were,preliminarily,multidimensionally,evaluated,provide,reference,basis,further,research,clinical,trial,results,showed,that,had,low,cytotoxicity,significant,ability,promoting,migration,proliferation,stronger,characteristics,which,shows,development,prospects,These,strategy
AB值:
0.516218
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