典型文献
Multimodal integrated strategy for the discovery and identification of quality markers in traditional Chinese medicine
文献摘要：
With the modernization and internationalization of traditional Chinese medicine(TCM),the requirement for quality control has increased.The quality marker(Q-marker)is an important standard in this field and has been implemented with remarkable success in recent years.However,the establishment of Q-markers remains fragmented and the process lacks systematicity,resulting in inconsistent quality control and insufficient correlation with clinical efficacy and safety of TCM.This review introduces four multi-modal integrated approaches that contribute to the discovery of more comprehensive and accurate Q-markers,thus aiding in the establishment of new quality control patterns based on the characteristics and principles of TCM.These include the whole-process quality control strategy,chemical-activity-based screening method,efficacy,safety,and consistent combination strategy,and TCM theory-guided approach.Furthermore,methodologies and representative examples of these strategies are described,and important future directions and questions in this field are also proposed.
文献关键词：
中图分类号：
作者姓名：
Xiaoyan Lu;Yanyan Jin;Yuzhen Wang;Yunlong Chen;Xiaohui Fan
作者机构：
Pharmaceutical Informatics Institute,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,310058,China;Innovation Center in Zhejiang University,State Key Laboratory of Component-Based Chinese Medicine,Hangzhou,310058,China;Jinhua Institute of Zhejiang University,Jinhua,Zhejiang,321016,China;Westlake Laboratory of Life Sciences and Biomedicine,Hangzhou,310058,China;Department of Pharmacy,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,310016,China;Hangzhou Children's Hospital,Hangzhou,310010,China
文献出处：
引用格式：
[1]Xiaoyan Lu;Yanyan Jin;Yuzhen Wang;Yunlong Chen;Xiaohui Fan-.Multimodal integrated strategy for the discovery and identification of quality markers in traditional Chinese medicine)[J].药物分析学报（英文）,2022(05):701-710
A类：
systematicity
B类：
Multimodal,integrated,strategy,discovery,identification,quality,markers,traditional,Chinese,medicine,With,modernization,internationalization,TCM,requirement,control,has,increased,important,standard,this,field,been,implemented,remarkable,success,recent,years,However,establishment,remains,fragmented,process,lacks,resulting,inconsistent,insufficient,correlation,clinical,efficacy,safety,This,review,introduces,four,multi,approaches,that,contribute,comprehensive,accurate,thus,aiding,new,patterns,characteristics,principles,These,include,whole,chemical,activity,screening,combination,theory,guided,Furthermore,methodologies,representative,examples,these,strategies,are,described,future,directions,questions,also,proposed
AB值：
0.582113
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