典型文献
Long-chain alkanol-alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma
文献摘要:
Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents(HDESs).These HDESs are liquid at room temperature and have low viscosity(<12.26 mPa-s),low polarity(lower than that of methanol,ChCl-based deep eutectic solvents and other reported HDESs),and low density(<0.928 g/mL).A simple one-pot method based on a novel HDES-water two-phase extraction system was constructed for the extraction of weak-polarity bioactive components,anthraquinones,from Rhei Radix et Rhizoma.This HDES-based new extraction method does not consume hazardous organic solvents and can obtain a total anthraquinone yield of 21.52 mg/g,which is close to that obtained by the Chinese pharmacopoeia method(21.22 mg/g)and considerably higher than those by other reported HDESs-based extraction methods(14.20-20.09 mg/g,p<0.01).The high extraction yield can be mainly attributed to the severe destruction of the RRR cell walls by the extraction system and the excellent dissolving ability of novel HDESs for anthraquinones.
文献关键词:
中图分类号:
作者姓名:
Anqi Huang;Wenwen Deng;Xiao Li;Qutong Zheng;Xuanxuan Wang;Yuxiu Xiao
作者机构:
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(Ministry of Education)^Wuhan University School of Pharmaceutical Sciences,Wuhan,430071,China;National 111 Center for Cellular Regulation and Molecular Pharmaceutics^School of Bioengineering and Food Science,Hubei University of Technology,Wuhan,Hubei,430068,China
文献出处:
引用格式:
[1]Anqi Huang;Wenwen Deng;Xiao Li;Qutong Zheng;Xuanxuan Wang;Yuxiu Xiao-.Long-chain alkanol-alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma)[J].药物分析学报(英文),2022(01):87-95
A类:
alkanol,anthraquinones,Rhei,HDESs,HDES,pharmacopoeia
B类:
Long,chain,alkyl,carboxylic,acid,viscosity,hydrophobic,deep,eutectic,solvents,pot,extraction,from,Radix,Rhizoma,Natural,long,were,used,prepare,novel,These,liquid,room,temperature,have,mPa,polarity,lower,that,methanol,ChCl,other,reported,density,simple,water,two,phase,system,was,constructed,weak,bioactive,components,This,new,does,not,consume,hazardous,organic,can,total,yield,which,close,obtained,by,Chinese,considerably,higher,those,methods,be,mainly,attributed,severe,destruction,RRR,walls,excellent,dissolving,ability
AB值:
0.429249
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