典型文献
Transcriptional Regulation of YP3680 by RovA and RcsAB in Yersinia pestis biovar Microtus
文献摘要：
Type-VI secretion system (T6SS) is a widespread bacteriophage-like complex in bacteria that participates in multiple physiological processes, including metal ion uptake, bacterial competition, and biofilm formation[1]. Yersinia pestis is the causative agent of plague. There are five T6SS gene clusters in Y. pestis CO92, among which only the YPO0499-YPO0516 locus was well investigated[1,2]. The expression of YPO0499-YPO0516 is induced at 26 °C, suggesting that it plays a possible role in the natural cycle of Y. pestis[2]. Deletion of YPO0499-YPO0516 alters the uptake and intracellular growth of Y. pestis in macrophages, which is dependent on the pre-grown temperature[2]. However, it has no effect on the virulence in murine and on the ability of the pathogen to infect fleas[2]. The Hcp-like protein encoded by YPO0502 was shown to be an autoagglutination factor involved in the bacterial interaction[3].
文献关键词：
中图分类号：
作者姓名：
LIU Lei;FANG Nan;LIU Wan Bing;HE Ying Yu;LIU Yan;ZHANG Yi Quan
作者机构：
Department of Transfusion Medicine, General Hospital of Central Theater Command of the PLA, Wuhan 430070,Hubei, China;The First School of Clinical Medicine, Southern Medical University, Guangzhou 510280, Guangdong, China;Beijing USCI Medical Laboratory Co., Ltd. Building C7, YiYuan Industrial Base, Beijing 100195, China;Department of Clinical Laboratory, Nantong Third Hospital Affiliated to Nantong University, Nantong 226006, Jiangsu, China
文献出处：
引用格式：
[1]LIU Lei;FANG Nan;LIU Wan Bing;HE Ying Yu;LIU Yan;ZHANG Yi Quan-.Transcriptional Regulation of YP3680 by RovA and RcsAB in Yersinia pestis biovar Microtus)[J].生物医学与环境科学（英文版）,2022(03):234-238,前插22
A类：
YP3680,RovA,RcsAB,pestis,biovar,Microtus,CO92,YPO0499,YPO0516,YPO0502,autoagglutination
B类：
Transcriptional,Regulation,by,Yersinia,Type,VI,secretion,system,T6SS,widespread,bacteriophage,like,complex,that,participates,multiple,physiological,processes,including,metal,uptake,bacterial,competition,biofilm,formation,causative,agent,plague,There,are,five,gene,clusters,among,which,only,locus,was,well,investigated,expression,induced,suggesting,plays,possible,role,natural,cycle,Deletion,alters,intracellular,growth,macrophages,dependent,grown,temperature,However,has,no,effect,virulence,murine,ability,pathogen,infect,fleas,Hcp,protein,encoded,shown,be,involved,interaction
AB值：
0.507006
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
