典型文献
Nitrogen starvation induces genome-wide activation of transposable elements in ArabidopsisFA
文献摘要：
Nitrogen (N) availability is a major limiting factor for plant growth and agricultural productivity. Al-though the gene regulation network in response to N starvation has been extensively studied, it re-mains unknown whether N starvation has an im-pact on the activity of transposable elements (TEs). Here, we report that TEs can be transcrip-tionally activated in Arabidopsis under N starva-tion conditions. Through genetic screening of idm1-14 suppressors, we cloned GLU1, which encodes a glutamate synthase that catalyzes the synthesis of glutamate in the primary N assim-ilation pathway. We found that glutamate syn-thase 1 (GLU1) and its functional homologs GLU2 and glutamate transport 1 (GLT1) are redundantly required for TE silencing, suggesting that N me-tabolism can regulate TE activity. Transcriptome and methylome analyses revealed that N starva-tion results in genome-wide TE activation without inducing obvious alteration of DNA methylation. Genetic analysis indicated that N starvation-induced TE activation is also independent of other well-established epigenetic mechanisms, in-cluding histone methylation and heterochromatin decondensation. Our results provide new insights into the regulation of TE activity under stressful environments in planta.
文献关键词：
中图分类号：
作者姓名：
Yue Wang;Yi Liu;Shaofeng Qu;Wenjie Liang;Linhua Sun;Dong Ci;Zhitong Ren;Liu-Min Fan;Weiqiang Qian
作者机构：
State Key Laboratory of Protein and Plant Gene Research,School of Advanced Agricultural Sciences,Peking University,Beijing 100871,China;School of Life Sciences,Peking University,Beijing 100871,China;Peking University Institute of Advanced Agricultural Sciences,Weifang 261000,China
文献出处：
引用格式：
[1]Yue Wang;Yi Liu;Shaofeng Qu;Wenjie Liang;Linhua Sun;Dong Ci;Zhitong Ren;Liu-Min Fan;Weiqiang Qian-.Nitrogen starvation induces genome-wide activation of transposable elements in ArabidopsisFA)[J].植物学报（英文版）,2022(12):2374-2384
A类：
ArabidopsisFA,starva,idm1,GLU1,assim,ilation,GLU2,GLT1,decondensation
B类：
Nitrogen,starvation,induces,genome,wide,activation,transposable,elements,availability,major,limiting,growth,agricultural,productivity,though,regulation,network,response,been,extensively,studied,mains,unknown,whether,pact,activity,TEs,Here,report,that,can,transcrip,tionally,activated,under,conditions,Through,screening,suppressors,cloned,which,encodes,glutamate,synthase,catalyzes,synthesis,primary,pathway,We,found,its,functional,homologs,transport,are,redundantly,required,silencing,suggesting,tabolism,regulate,Transcriptome,methylome,analyses,revealed,results,without,inducing,obvious,alteration,methylation,Genetic,analysis,indicated,induced,also,independent,other,well,established,epigenetic,mechanisms,cluding,histone,heterochromatin,Our,provide,new,insights,into,stressful,environments,planta
AB值：
0.536491
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
