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典型文献
R-loop:The new genome regulatory element in plantsFA
文献摘要:
An R-loop is a three-stranded chromatin struc-ture that consists of a displaced single strand of DNA and an RNA:DNA hybrid duplex, which was thought to be a rare by-product of tran-scription. However, recent genome-wide data have shown that R-loops are widespread and pervasive in a variety of genomes, and a growing body of experimental evidence in-dicates that R-loops have both beneficial and harmful effects on an organism. To maximize benefit and avoid harm, organisms have evolved several means by which they tightly regulate R-loop levels. Here, we summarize our current understanding of the biogenesis and effects of R-loops, the mechanisms that regu-late them, and methods of R-loop profiling, re-viewing recent research advances on R-loops in plants. Furthermore, we provide perspectives on future research directions for R-loop biology in plants, which might lead to a more compre-hensive understanding of R-loop functions in plant genome regulation and contribute to fu-ture agricultural improvements.
文献关键词:
作者姓名:
Jincong Zhou;Weifeng Zhang;Qianwen Sun
作者机构:
Center for Plant Biology,School of Life Sciences,Tsinghua University,Beijing 100084,China;Tsinghua-Peking Center for Life Sciences,Beijing 100084,China
引用格式:
[1]Jincong Zhou;Weifeng Zhang;Qianwen Sun-.R-loop:The new genome regulatory element in plantsFA)[J].植物学报(英文版),2022(12):2275-2289
A类:
plantsFA
B类:
new,regulatory,element,An,three,stranded,chromatin,struc,that,consists,displaced,single,hybrid,duplex,which,was,thought,rare,by,product,scription,However,recent,data,have,shown,loops,widespread,pervasive,variety,genomes,growing,body,experimental,evidence,dicates,both,beneficial,harmful,effects,To,maximize,benefit,avoid,organisms,evolved,several,means,they,tightly,regulate,levels,Here,summarize,our,current,understanding,biogenesis,mechanisms,them,methods,profiling,viewing,research,advances,Furthermore,provide,perspectives,future,directions,biology,might,lead,compre,hensive,functions,regulation,contribute,agricultural,improvements
AB值:
0.56838
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