典型文献
Recent advancements toward non-invasive imaging of retinal amyloid-beta for early detection of Alzheimer 's disease
文献摘要：
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive impairment suggested to be induced by the accumulation of amyloid-β (Aβ) in the brain, especially in the hippocampus. Cerebral Aβ deposits may be detected through positron emission tomography (PET) as early as two decades before clinically diagnosed AD-associated dementia, which provides the opportunity for early therapeutic interventions (Wang and Mao, 2021). PET may not be suitable for AD screening since it is invasive, costly, and inaccessible for routine clinical use or population screening. Aβ deposits have also been identified throughout the retina, which is a developmental outgrowth of the diencephalon and shares physiological and pathological pathways with the central nervous system (London et al., 2013).
文献关键词：
中图分类号：
作者姓名：
Liang Wang;Xiaobo Mao
作者机构：
University of Miami Miller School of Medicine, Miami,FL,USA;Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering,Department of Neurology,Johns Hopkins University School of Medicine,Baltimore,MD,USA
文献出处：
引用格式：
[1]Liang Wang;Xiaobo Mao-.Recent advancements toward non-invasive imaging of retinal amyloid-beta for early detection of Alzheimer 's disease)[J].中国神经再生研究（英文版）,2022(08):1741-1742
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diencephalon
B类：
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0.663255
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